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This disease in humans is usually caused by "Demodex folliculorum" (not the same species affecting dogs) and is usually called demodicosis which may have a rosacea-like appearance. Common symptoms include hair loss, itching and inflammation. An association with pityriasis folliculorum has also been described.
Demodicosis is most often seen in folliculitis (inflammation of the hair follicles of the skin). Depending on the location it may be a small pustules (pimples or pustules) at the exit of hair, placed on inflamed, congested skin. Demodicosis is accompanied by itching, swelling and erythema of the eyelid margins, the appearance of scales at the base of the eyelashes. Typically, patients complain of eyestrain. Characteristic of view of the affected century: plaque on the edge of the eyelids, eyelashes stuck together, surrounded by crusts as a clutch.
Scaly foot causes lesions of the skin with dermatitis and thickening of the skin.
Commonly known as scaly face, scaly legs, or tassel foot, knemidocoptiasis affects primarily the face and legs of birds around the world worldwide and can be fatal.
Sarcoptic mange, also known as canine scabies, is a highly contagious infestation of "Sarcoptes scabiei canis", a burrowing mite. The canine sarcoptic mite can also infest cats, pigs, horses, sheep, and various other species. The human analog of burrowing mite infection, due to a closely related species, is called scabies (the "seven year itch").
All these burrowing mites are in the family Sarcoptidae. They dig into and through the skin, causing intense itching from an allergic reaction to the mite, and crusting that can quickly become infected. Hair loss and crusting frequently appear first on elbows and ears. Skin damage can occur from the dog's intense scratching and biting. Secondary skin infection is also common. Dogs with chronic sarcoptic mange are often in poor condition, and in both animals and humans, immune suppression from starvation or any other disease causes this type of mange to develop into a highly crusted form in which the burden of mites is far higher than in healthy specimens.
Scaly foot, otherwise known as knemidocoptiasis, is caused by burrowing mites in the genus "Knemidocoptes". The condition can be compared with sarcoptic mange in mammals, but does not seem to cause the same level of itching. The birds chiefly affected are galliformes (chickens and turkeys), passerines (finches, canaries, sparrows, robins, wrens), and psittacine birds (parrots, macaws, parakeets, budgerigars). The condition sometimes additionally affects piciformes (woodpeckers, toucans) and anseriformes ducks, geese, swans), raptors and other birds. The two species of mite most often implicated are "K. jamaicensis" and "K. intermedius". Other related species of mite affect feather follicles and cause depluming. The mites are mostly transmitted by prolonged direct contact, particularly from parent bird to unfledged nestling.
Mange is a class of skin diseases caused by parasitic mites. Since mites also infect plants, birds, and reptiles, the term "mange", suggesting poor condition of the hairy coat due to the infection, is sometimes reserved only for pathological mite-infestation of nonhuman mammals. Thus, mange includes mite-associated skin disease in domestic animals (cats and dogs), in livestock (such as sheep scab), and in wild animals (for example, coyotes, cougars, and bears). Since mites belong to the arachnid subclass Acari (also called Acarina), another term for mite infestation is acariasis.
Parasitic mites that cause mange in mammals embed themselves either in skin or hair follicles in the animal, depending upon their genus. "Sarcoptes" spp. burrow into skin, while "Demodex" spp. live in follicles.
In humans, these two types of mite infections, which would otherwise be known as "mange" in furry mammals, are instead known respectively as scabies and demodicosis.
The characteristic symptoms of a scabies infection include intense itching and superficial burrows. The burrow tracks are often linear, to the point that a neat "line" of four or more closely placed and equally developed mosquito-like "bites" is almost diagnostic of the disease. Because the host develops the symptoms as a reaction to the mites' presence over time, typically a delay of four to six weeks occurs between the onset of infestation and the onset of itching. Similarly, symptoms often persist for one to several weeks after successful eradication of the mites. As noted, those re-exposed to scabies after successful treatment may exhibit symptoms of the new infestation in a much shorter period—as little as one to four days.
The superficial burrows of scabies usually occur in the area of the finger webs, feet, ventral wrists, elbows, back, buttocks, and external genitals. Except in infants and the immunosuppressed, infection generally does not occur in the skin of the face or scalp. The burrows are created by excavation of the adult mite in the epidermis.
In most people, the trails of the burrowing mites are linear or S-shaped tracks in the skin often accompanied by rows of small, pimple-like mosquito or insect bites. These signs are often found in crevices of the body, such as on the webs of fingers and toes, around the genital area, in stomach folds of the skin, and under the breasts of women.
Symptoms typically appear two to six weeks after infestation for individuals never before exposed to scabies. For those having been previously exposed, the symptoms can appear within several days after infestation. However, symptoms may appear after several months or years. Acropustulosis, or blisters and pustules on the palms and soles of the feet, are characteristic symptoms of scabies in infants.
Demodicosis, also called demodectic mange or red mange, is caused by a sensitivity to and overpopulation of "Demodex canis" as the hosts immune system is unable to keep the mites under control.
"Demodex" is a genus of mite in the family Demodicidae. "Demodex canis" occurs naturally in the hair follicles of most dogs in low numbers around the face and other areas of the body. In most dogs, these mites never cause problems. However, in certain situations, such as an underdeveloped or impaired immune system, intense stress, or malnutrition, the mites can reproduce rapidly, causing symptoms in sensitive dogs that range from mild irritation and hair loss on a small patch of skin to severe and widespread inflammation, secondary infection, and in rare cases can be a life-threatening condition. Small patches of demodicosis often correct themselves over time as the dog's immune system matures, although treatment is usually recommended.
Infections on the body may give rise to typical enlarging raised red rings of ringworm. Infection on the skin of the feet may cause athlete's foot and in the groin, jock itch. Involvement of the nails is termed onychomycosis, and they may thicken, discolour, and finally crumble and fall off. They are common in most adult people, with up to 20% of the population having one of these infections at any given moment.
Animals such as dogs and cats can also be affected by ringworm, and the disease can be transmitted between animals and humans, making it a zoonotic disease.
Specific signs can be:
- red, scaly, itchy or raised patches
- patches may be redder on outside edges or resemble a ring
- patches that begin to ooze or develop blister
- bald patches may develop, when the scalp is affected
- nails may thicken, discolour or begin to crack
Ear mites are mites that live in the ears of animals and humans. The most commonly seen species in veterinary medicine is "Otodectes cynotis" (Gk. oto=ear, dectes=biter, cynotis=of the dog). This species, despite its name, is also responsible for 90% of ear mite infections in cats.
In veterinary practice, ear mite infections in dogs and cats may present as a disease that causes intense itching in one or both ears, which in turn triggers scratching at the affected ear. An unusually dark colored ear wax (cerumen) may also be produced. Cats, as well as dogs with erect ears that have control over ear direction, may be seen with one or both ear pinnas held at an odd or flattened angle.
The most common lesion associated with ear mites is an open or crusted ("scabbed") skin wound at the back or base of the ear, caused by abrasion of the skin by hind limb claws, as the ear has been scratched in an attempt to relieve the itching. This lesion often becomes secondarily infected and crusted from ordinary skin bacteria, so that the common presentation of ear mites is such a wound appearing on the back or base of one or both ears. This is accompanied by the Pinnal-Pedal Reflex that appears as reflex scratching motions of the hind limb when the ear is manipulated (this test is positive as well in other mite infections of the outside and rim of the ear pinnas in mange). When the ear mite infection is treated, such wounds resolve spontaneously, and this resolution may be speeded with application of topical antibiotics.
The most common ear mite (as well as mange mite) treatments currently use the antiparasitics ivermectin and selamectin, usually as topical preparations. Ivermectin is available as a direct water-based liquid that is squeezed into the ear canal and massaged at the base of the ear to distribute the medication. Selamectin is available as a once-a-month preparation that can be applied to the animal's skin, which prevents mite infestation over that time.
The most common term for the infection, "ringworm", is a misnomer, since the condition is caused by fungi of several different species and not by parasitic worms.
The rabbit ear mite, "Psoroptes cuniculi", is larger than "Otodectes cynotis". It causes thick firm debris to form in the ear canal, and can eventually migrate to the skin of the outer ear and face. Symptoms include scratching and shaking of the head. Treatment includes topical selamectin, or injections of ivermectin and frequent cleanings of the rabbit's environment.
Flea allergy dermatitis, FAD, is an eczematous itchy skin disease of dogs and cats. For both of these domestic species, flea allergy dermatitis is the most common cause of skin disease. Affected animals develop allergic reactions to chemicals in flea saliva. Symptoms of this reaction include erythema (redness), papules (bumps), pustules (pus-filled bumps), and crusts (scabs). If severe, hair loss will occur in the affected area. Dogs with flea allergy dermatitis often show hair loss and eczematous skin rash on the lower back, upper tail, neck, and down the back of the legs. Cats with flea allergy dermatitis may develop a variety of skin problems, including feline eosinophilic granuloma, miliary dermatitis, or self-inflicted alopecia from excessive grooming.
The flea found most commonly on both dogs and cats with a flea infestation is the cat flea, "Ctenocephalides felis". Pets that develop FAD have an allergic response to flea saliva injected during flea feeding. The itch associated with just one flea bite persists long after that flea is gone and leads to significant self-trauma.
Most of the mites which cause this affliction to humans are from the order Acari, hence the name Acariasis. The entire taxonomic classification to order would be:
- Kingdom: Animalia
- Phylum: Arthropoda
- Subphylum: Chelicerata
- Class: Arachnida
- Order: Acari (At the order level, there is still substantial argument among researchers as to how to categorize Acari. Some call it a subclass, others a superorder, "Acarina".)
Specific species involved include:
- Acariformes
- Trombidiformes
- "Trombicula" species (trombiculosis or chiggers)
- "Demodex" species (Demodicosis)
- "Pyemotes tritici"
- "Cheyletiella"
- Sarcoptiformes
- "Sarcoptes scabiei" (Scabies)
- Parasitiformes
- "Dermanyssus gallinae"
- "Liponyssoides sanguineus"
- "Ornithonyssus bacoti", "Ornithonyssus bursa", "Ornithonyssus sylviarum"
- Another candidate is "Androlaelaps casalis". However, based on this mite's life style as a predator on other mite species (such as the previously-mentioned "Dermanyssus gallinae"), it is highly unlikely to be a cause of acariasis.
Some of these reflect reports existing of human infestation by mites previously believed not to prey on humans.
A hot spot, or "acute moist dermatitis", is an acutely inflamed and infected area of skin irritation created and made worse by a dog licking and biting at itself. A hot spot can manifest and spread rapidly in a matter of hours as secondary Staphylococcus infection causes the top layers of the skin to break down and as pus becomes trapped in the hair. Hot spots can be treated with corticosteroid medications and oral as well as topical antibiotic application, as well as clipping hair from around the lesion. Underlying inciting causes include flea allergy dermatitis, ear disease or other allergic skin diseases. Dogs with thick undercoat are most subject to getting hot spots.
There are several complications with the terminology:
Acariasis is a term for a rash, caused by mites, sometimes with a papillae (pruritic dermatitis), and usually accompanied by severe itching sensations. An example of such an infection is scabies.
The closely related term, mange, is commonly used with domestic animals (pets) and also livestock and wild mammals, whenever hair-loss is involved. "Sarcoptes" and "Demodex" species are involved in mange, but both of these genera are also involved in human skin diseases (by convention only, not called mange). "Sarcoptes" in humans is especially severe symptomatically, and causes the condition scabies noted above.
Another genus of mite which causing itching but rarely causes hair loss because it burrows only at the keratin level, is "Cheyletiella." Various species of this genus of mite also affect a wide variety of mammals, including humans.
Mite infestation sometimes implies an ectoparasitic, cutaneous condition such as dermatitis. However, it is possible for mites to invade the gastrointestinal and urinary tracts.
MeSH uses the term "Mite Infestations" as pertaining to Acariformes. However, mites not in this grouping can be associated with human disease. (See "Classification", below.)
The term Acari refers to ticks and mites together, which can cause ambiguity. (Mites are a paraphyletic grouping).
Mites can be associated with disease in at least three different ways: (1) cutaneous dermatitis, (2) production of allergin, and (3) as a vector for parasitic diseases. The language used to describe mite infestation often does not distinguish among these.
Sporotrichosis can be diagnosed in domestic and wild mammals. In veterinary medicine it is most frequently seen in cats and horses. Cats have a particularly severe form of cutaneous sporotrichosis and also can serve as a source of zoonotic infection to persons who handle them and are exposed to exudate from skin lesions.
Pemphigus foliaceus is the most common autoimmune disease of the dog. Blisters in the epidermis rapidly break to form crusts and erosions most often affecting the face and ears initially, but in some cases spreading to include the whole body. The pawpads can be affected causing marked hyperkeratosis (thickening of the pads with scale). Other autoimmune diseases include bullous pemphigoid and epidermolysis bullosa acquisita.
Treatment of autoimmune skin conditions requires treatment to markedly reduce the abnormal immune response; steroids, azathoprine and other drugs are used as immunosuppressive agents.
Mud fever, also known as scratches or pastern dermatitis, is a group of diseases of horses causing irritation and dermatitis in the lower limbs of horses. Often caused by a mixture of bacteria, typically "Dermatophilus congolensis", and "Staphylococcus spp", mud fever can also be caused by fungal organisms (dermatophytes). Photosensitization, chorioptic mange mites, contact dermatitis and other conditions also contribute to some cases. This condition is also known as "dew poisoning," "grease heel," or "greasy heel".
Mud fever affects most horses and ponies during winter and early spring, resulting in painful sores and scabs, which in severe cases can make a horse lame. Mud fever most commonly affects the pastern and heel area but can also affect the upper leg, the belly, and in some cases the neck area (also known as Rain Scald). Non-pigmented skin tends to be more severely affected.
Cat skin disorders are among the most common health problems in cats.
Skin disorders in cats have many causes, and many of the common skin disorders that afflict people have a counterpart in cats. The condition of a cat's skin and coat can also be an important indicator of its general health. Skin disorders of cats vary from acute, self-limiting problems to chronic or long-lasting problems requiring life-time treatment. Cat skin disorders may be grouped into categories according to the causes.
Sporotrichosis (also known as "rose gardener's disease") is a disease caused by the infection of the fungus "Sporothrix schenckii". This fungal disease usually affects the skin, although other rare forms can affect the lungs, joints, bones, and even the brain. Because roses can spread the disease, it is one of a few diseases referred to as "rose-thorn" or "rose-gardeners' disease".
Because "S. schenckii" is naturally found in soil, hay, sphagnum moss, and plants, it usually affects farmers, gardeners, and agricultural workers. It enters through small cuts and abrasions in the skin to cause the infection. In case of sporotrichosis affecting the lungs, the fungal spores enter through the respiratory pathways. Sporotrichosis can also be acquired from handling cats with the disease; it is an occupational hazard for veterinarians.
Sporotrichosis progresses slowly – the first symptoms may appear 1 to 12 weeks (average 3 weeks) after the initial exposure to the fungus. Serious complications can also develop in patients who have a compromised immune system.
Mud fever is a chronic but progressive dermatitis. It affects all breeds of horses, but it is most common in heavy draft horses like the Clydesdales. It often starts as a small red ulceration of the skin in the plantar pastern region of the legs. The lesions then grow and develop scaling with the formation of a crust, hair loss, edema, oozing and the release of a malodorous exudate. Skin fissures and papillomatous lesions can develop in chronic cases.
Some diseases are inherent abnormalities of skin structure or function. These include skin fragility syndrome (Ehlers-Danlos), hereditary hypotrichosis and congenital or hereditary alopecia.
Cats with eosinophilic granuloma complex (EGC) may have one or more of four patterns of skin disease.
The most frequent form is "eosinophilic plaque". This is a rash comprising raised red to salmon-colored and flat-topped, moist bumps scattered on the skin surface. The most common location is on the ventral abdomen and inner thigh.
Another form of EGC is the "lip ulcer". This is a painless, shallow ulcer with raised and thickened edges that forms on the upper lip adjacent to the upper canine tooth. It is often found on both sides of the upper lips.
The third form of the EGC is the "collagenolytic granuloma". This is a firm swelling that may be ulcerated. The lesions may form on the skin, especially of the face, in the mouth, or on the feet, or may form linear flat-topped raised hairless lesions on the back of the hind legs, also called "linear granuloma".
The least common form of EGC is "atypical eosinophilic dermatitis". It is unique in that it is caused by mosquito bite allergy and the lesions form on the parts of the body with the least hair affording easy access to feeding mosquitoes. This includes the bridge of the nose, the outer tips of the ears and the skin around the pads of the feet. The lesions are red bumps, shallow ulcers and crusts.