Sexophobia in clinical talk has an effect on the way patients speak to their doctors, as it manifests itself in the communication strategies that are employed to speak about private health problems. In that sense, the use of neutral and veiled vocabulary by doctors can discourage patients to speak openly about their sexual issues.

Otherwise, historian and sociologist Cindy Patton has identified sexophobia as one of the main trends that characterised the development of the second phase of the VIH epidemics in Great Britain, along with homophobia and germophobia.

Homophobic attitudes and behaviors may be linked to sexophobia: doctor Martin Kantor describes many homophobes as being basically sexophobes, who fear and loathe sexual relationships both between partners of the same sex and between heterosexual partners.