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MAV is not recognized as a distinct diagnostic entity. Lembert and Neuhauser propose criteria for definite and probable migraine-associated vertigo.
A diagnosis of "definite migraine-associated vertigo" includes a case history of:
- episodic vestibular symptoms of at least moderate severity;
- current or previous history of migraine according to the 2004 "International Classification of Headache Disorders";
- one of the following migrainous symptoms during two or more attacks of vertigo: migrainous headache, photophobia, phonophobia, visual or other auras; and
- other causes ruled out by appropriate investigations.
A diagnosis of "probable migraine-associated vertigo" includes a case history of episodic vestibular symptoms of at least moderate severity and one of the following:
- current or previous history of migraine according to the 2004 "International Classification of Headache Disorders";
- migrainous symptoms during vestibular symptoms;
- migraine precipitants of vertigo in more than 50% of attacks, such as food triggers, sleep irregularities, or hormonal change;
- response to migraine medications in more than 50% of attacks; and
- other causes ruled out by appropriate investigations.
Note that, in both of the above criteria, headache is not required to make the diagnosis of migraine-associated vertigo.
They add that, in patients with a clear-cut history, no vestibular tests are required. Other historical criteria which are helpful in making the diagnosis of migraine-associated vertigo are vertiginous symptoms throughout the patient’s entire life, a long history of motion intolerance, sensitivity to environmental stimuli, illusions of motion of the environment, and vertigo that awakens the patient.
Treatment of migraine-associated vertigo is the same as the treatment for migraine in general.
The diagnostic criteria as of 2015 define definite MD and probable MD as follows:
Definite
1. Two or more spontaneous episodes of vertigo, each lasting 20 minutes to 12 hours
2. Audiometrically documented low- to medium-frequency sensorineural hearing loss in the affected ear on at least 1 occasion before, during, or after one of the episodes of vertigo
3. Fluctuating aural symptoms (hearing, tinnitus, or fullness) in the affected ear
4. Not better accounted for by another vestibular diagnosis
Probable
1. Two or more episodes of vertigo or dizziness, each lasting 20 minutes to 24 hours
2. Fluctuating aural symptoms (hearing, tinnitus, or fullness) in the reported ear
3. Not better accounted for by another vestibular diagnosis
A common and important symptom of MD is hypersensitivity to sounds. This hypersensitivity is easily diagnosed by measuring the loudness discomfort levels (LDLs).
Symptoms of MD overlap with migraine-associated vertigo (MAV) in many ways, but when hearing loss develops in MAV is usually in both ears, and this is rare in MD, and hearing loss generally does not progress in MAV as it does in MD.
People who have had a transient ischemic attack (TIA) and stroke can present with symptoms similar to MD, and in people at risk for stroke magnetic resonance imaging (MRI) should be conducted to exclude TIA or stroke, and as TIA is often a precursor to stroke, that risk should be managed.
Other vestibular conditions that should be excluded include vestibular paroxysmia, recurrent unilateral vestibulopathy, vestibular schwannoma, or a tumor of the endolymphatic sac.
From 3% to 11% of diagnosed dizziness in neuro-otological clinics are due to Meniere's. The annual incidence rate is estimated to be about 15/100,000 and the prevalence rate is about 218/100,000, and around 15% of people with Meniere's disease are older than 65. In around 9% of cases a relative also had MD, signalling that there may be a genetic predisposition in some cases.
The odds of MD are greater for people of white ethnicity, with severe obesity, and women. Several conditions are often comorbid with MD, including arthritis, psoriasis, gastroesophageal reflux disease, irritable bowel syndrome, and migraine.