Autophobia is a form of anxiety that can cause a minor to extreme feeling of danger or fear when alone. There is not a specific treatment to cure autophobia as it affects each person differently. Most sufferers are treated with psychotherapy in which the amount of time that they are alone is slowly increased. There are no conclusive studies currently that support any medications being used as treatment. If the anxiety is too intense medications have been used to aid the patient in a continuation of the therapy.

It is not uncommon for sufferers to be unaware that they have this anxiety and to dismiss the idea of seeking help. Much like substance abuse, autophobia is mental and physical and requires assistance from a medical professional. Medication can be used to stabilize symptoms and inhibit further substance abuse. Group and individual therapy is used to help ease symptoms and treat the phobia.

In mild cases of autophobia, treatment can sometimes be very simple. Therapists recommend many different remedies to make patients feel as though they are not alone even when that is the case, such as listening to music when running errands alone or turning on the television when at home, even if it is just for background noise. Using noise to interrupt the silence of isolated situations can often be a great help for people suffering from autophobia.

However, it is important to remember that just because a person may feel alone at times does not mean that they have autophobia. Most people feel alone and secluded at times; this is not an unusual phenomenon. Only when the fear of being alone beings to interrupt how a person lives their daily life does the idea of being autophobic become a possibility.

Autophobia, also called monophobia, isolophobia, or eremophobia, is the specific phobia of isolation; a morbid fear of being egotistical, or a dread of being alone or isolated. Sufferers need not be physically alone, but just to believe that they are being ignored or unloved. Contrary to what would be implied by a literal reading of the term, "autophobia" does not describe a "fear of oneself". The disorder typically develops from and is associated with other anxiety disorders.

Autophobia can be associated with or accompanied by several other phobias such as agoraphobia, and is generally considered to be a part of the agoraphobic cluster. This means that autophobia has a lot of the same characteristics as certain anxiety disorders and hyperventilation disorders. The main concern of people with phobias in the agoraphobic cluster is getting help in case of emergency. This means people might be afraid of going out in public, being caught in a crowd, being alone, or being stranded.

Autophobia is not to be confused with agoraphobia (fear of being in public, or caught in large crowds), self-hatred, or social anxiety although it can be closely related to these things. It is its own phobia that tends to be accompanied by other anxiety disorders and phobias.

Like many other phobias, lilapsophobia can often be treated using cognitive-behavioral therapy, but if it stems from post-traumatic stress disorder, then alternative therapy may be more recommended.

Like astraphobia, lilapsophobia is a common fear for children, although less common. Because children are just learning to distinguish between fantasy and reality, major storm broadcasts on television or discussion by parents can cause fear that the storm is coming with a tornadic potential or a hurricane.

Because fear is a part of normal child development, this phobia is not diagnosed unless if persisted for more than six months. Parents should conquer the child's fear by telling them how rare the major storms that hit hometown area are.

Data from the 2001–02 National Epidemiologic Survey on Alcohol and Related Conditions indicates a prevalence rate of 2.36% in the American general population. It appears to occur with equal frequency in males and females. In one study, it was seen in 14.7% of psychiatric outpatients.

Being a personality disorder, which are usually chronic and long-lasting mental conditions, avoidant personality disorder is not expected to improve with time without treatment. It is a poorly studied personality disorder and in light of prevalence rates, societal costs, and the current state of research, AvPD qualifies as a neglected disorder.