Anesthesia fetish is considered edgeplay when realised outside the boundaries of fantasy, and may result in various degrees of harm, or death. Fantasies are elaborated by the viewing of images and reading of stories of anesthetic inductions. Edgeplay may involve obtaining and scening with various anesthesia-related paraphernalia—usually anesthesia masks for breathplay, the acquisition of anesthetics for anesthetizing others or being anesthetized oneself, and the occupation of a medical setting or environment for the same practice.

Some anesthesia fetishists who seek to be anesthetized may feign or induce medical conditions in an attempt to obtain general anesthesia from medical personnel. This is considered safer than playing with anesthetic agents outside of a medical setting, but may nevertheless be an abuse of all concerned.

The Internet has enabled people with this relatively rare paraphilia to discuss the subject and exchange anesthesia-related multimedia.

Abasiophilia plays a prominent role in the Michael Connelly novel "The Scarecrow", in which a serial killer is motivated by abasiophilia.

Abasiophilia is a psychosexual attraction to people with impaired mobility, especially those who use orthopaedic appliances such as leg braces, orthopedic casts, or wheelchairs. The term abasiophilia was first used by John Money of the Johns Hopkins University in a paper on paraphilias in 1990.