The cause is the most mysterious aspect of the disease. Commentators then and now put much blame on the generally poor sanitation, sewage and contaminated water supplies of the time, which might have harboured the source of infection. The first outbreak at the end of the Wars of the Roses means that it may have been brought over from France by the French mercenaries whom Henry VII used to gain the English throne. However, the "Croyland Chronicle" mentions that Thomas Stanley, 1st Earl of Derby used the "sweating sickness" as an excuse not to join with Richard III's army prior to the Battle of Bosworth.

Relapsing fever has been proposed as a possible cause. This disease, which is spread by ticks and lice, occurs most often during the summer months, as did the original sweating sickness. However, relapsing fever is marked by a prominent black scab at the site of the tick bite and a subsequent skin rash.

Noting symptom overlap with hantavirus pulmonary syndrome, several scientists proposed an unknown hantavirus as the cause. A critique of this hypothesis included the argument that, whereas sweating sickness was thought to be transmitted from human to human, hantaviruses are rarely spread in this way. However, infection via human-to-human contact has been proven in hantavirus outbreaks in Argentina.

Sweating sickness, also known as "English sweating sickness" or "English sweate" (), was a mysterious and highly contagious disease that struck England, and later continental Europe, in a series of epidemics beginning in 1485. The last outbreak occurred in 1551, after which the disease apparently vanished. The onset of symptoms was dramatic and sudden, death often occurring within hours. Although its cause remains unknown, it has been suggested that an unknown species of hantavirus was responsible for the outbreak.

The Picardy sweat was an infectious disease of unknown cause. It appeared in the northern French province of Picardy in 1718. Between 1718 and 1874, 194 epidemics of the Picardy sweat were recorded. The last extensive outbreak was in 1906, which a French commission attributed to fleas from field mice. A subsequent case was diagnosed in 1918 in a soldier in Picardy.

It was named "suette des Picards" in France, and "picard'scher Schweiß" or "picard'sches Schweissfieber" in Germany. There were several longer descriptions of the disease.

The disease was similar to the English sweat but differed in some symptoms and in its course and mortality rate. Some of the symptoms were high fever, rash, and bleeding from the nose. Many victims died within two days.

As of 2017 there is no commercially available vaccine. A vaccine has been in development for scrub typhus known as the scrub typhus vaccine.

It has been said by many dog owners that limber tail had been caused shortly (24 hours) after swimming in water that is too cold or on rare occasions too warm and indeed this has certainly produced this very condition. The actual cause is unknown but it may be caused by the narrowing of the space through which the spinal cord passes, typically due to degenerative change to the intervertebral disk spaces. These underlying changes may not lead to visible change until the problem is suddenly exacerbated, such as during physical activity, after trauma, etc. Occasionally other changes are seen prior to or in conjunction with limber tail disease, such as urinary or fecal incontinence, postural abnormalities in the pelvic limb, or pain in response to touching the lower back.

With rest, the tail returns to normal within a few days. Pain relief, such as a nonsteroidal anti-inflammatory drug may be administered. The symptoms may reoccur.

The American Public Health Association recommends treatment based upon clinical findings and before culturing confirms the diagnosis. Without treatment, death may occur in 10 to 60 percent of patients with epidemic typhus, with patients over age 60 having the highest risk of death. In the antibiotic era, death is uncommon if doxycycline is given. In one study of 60 hospitalized patients with epidemic typhus, no patient died when given doxycycline or chloramphenicol. Some patients also may need oxygen and intravenous (IV) fluids.

Meteoropathy (from Greek "meteora", celestial phenomena, and "pathos", feeling, pain, suffering) is a physical condition, or symptom associated with weather conditions such as humidity, temperature or pressure.

A lallation (also called cambia-letras or troca-letra, "letter changer", in Latin American countries) is an imperfect enunciation of the letter "L", in which it sounds like "R" (or vice versa), as frequently found in infantile speech.

The speech pattern has been particularly associated with the use of the Portuguese, Spanish and English languages by Chinese, Korean, and Japanese people. The use of lallation has thus been a common feature of Western stereotypes of East Asian people. It is also common among English-speakers in parts of East Africa.

Devon colic was a condition that affected people in the English county of Devon during parts of the 17th and 18th centuries, before it was discovered to be lead poisoning.

The first written account of the colic comes from 1655. Symptoms began with severe abdominal pains and the condition was occasionally fatal. Cider is the traditional drink of Devonians, and the connection between the colic and cider drinking had been observed for many years. The condition was commonly attributed to the acidity of the beverage.

William Musgrave's publication "De arthritide symptomatica" (2nd edn, 1715) included the first scientific description of "Devonshire colic" – it was later referred to by John Huxham and Sir George Baker.

However, the precise cause was not discovered until the 1760s when Dr George Baker put forward the hypothesis that poisoning from lead in cider was to blame. He observed that the symptoms of the colic were similar to those of lead poisoning. He pointed out that lead was used in the cider making process both as a component of the cider presses and in the form of lead shot which was used to clean them. He also conducted chemical tests to demonstrate the presence of lead in Devon apple juice.

The publication of his results met with some hostile reaction from cider manufacturers, keen to defend their product. Once Baker's conclusions became accepted and the elimination of lead from the cider presses was undertaken, the colic declined. By 1818, Baker's son reported that it was "hardly known to exist" in Devon.

Meteoropathy is different from historical conceptions of "air" causing diseases and strongly influencing people's sense of well-being (see Miasma theory of disease).

""Pleasant weather (higher temperature or barometric pressure) was related to higher mood, better memory, and ‘‘"broadened"’’ cognitive style during the spring as time spent outside increased. The same relationships between mood and weather were not observed during other times of year, and indeed hotter weather was associated with lower mood in the summer.""

Of the simple phobias, aquaphobia is among the more common subtypes. In an article on anxiety disorders, Lindal and Stefansson suggest that aquaphobia may affect as many as 1.8% of the general Icelandic population, or roughly one in fifty people.

Anastasia and Tatiana Dogaru

born August 29, 2004) are craniopagus conjoined twins. They were scheduled to begin the first of several surgeries to separate them at Rainbow Babies and Children's Medical Center in Cleveland, Ohio. However, in August 2007 the surgery was called off as too dangerous.

The twins were born in Rome, Italy to Romanian parents, Alin Dogaru, a Byzantine Catholic priest, and Claudia Dogaru, a nurse. Their mother heard about the successful separation of Egyptian-born twins who were also joined at the head and hoped her children could also be successfully separated. The Dogaru family — who also have an older daughter, Maria, and younger son Theodor — were brought to north Texas by the World Craniofacial Foundation to have Anastasia and Tatiana evaluated for possible separation.

The girls are currently developing normally for their age and speak both Romanian and English. They get around with Anastasia leading the way and Tatiana following. The top of Tatiana's head is attached to the back of Anastasia's. Anastasia, whose kidneys don't function, relies on her sister's kidneys, and Tatiana on her sister's circulatory system. The girls also share blood flow to the back of the brain and some brain matter. Doctors estimated the twins had only a 50 percent chance of surviving the surgery. There were also risks of complications, such as brain damage, but the girls also risk early death if they remain conjoined. Their parents believed separation would give them their best chance at living a normal life.

In May 2007, doctors used a catheter to insert wire coils into the veins of the two girls, successfully redirecting their blood flow. It was the first time the procedure was attempted in conjoined twins. Doctors pushed back the first of the planned separation surgeries to June 2007 while studying the complex circulatory system of the twins, but, in August of that year, decided it was too risky.

Psychologists indicate that aquaphobia manifests itself in people through a combination of experiential and genetic factors. In the case of a 37 year old media professor, he noted that his fear initially presented its self as a, "severe pain, accompanied by a tightness of his forehead". In addition to this he experienced a choking sensation, discrete panic attacks and a reduction in his intake of fluids. These manifestations can have a profound effect on a persons health, work, confidence and overall well being.

Pneumonoultramicroscopicsilicovolcanoconiosis () is a word invented by the president of the National Puzzlers' League as a synonym for the disease known as silicosis. It is the longest word in the English language published in a dictionary, the "Oxford English Dictionary", which defines it as "an artificial long word said to mean a lung disease caused by inhaling very fine ash and sand dust."

Silicosis is a form of occupational lung disease caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in the form of nodular lesions in the upper lobes of the lungs. It is a type of pneumoconiosis.

Refusal of work is behavior which refuses to adapt to regular employment.

As actual behavior, with or without a political or philosophical program, it has been practiced by various subcultures and individuals. Radical political positions have openly advocated refusal of work. From within Marxism it has been advocated by Paul Lafargue and the Italian workerist/autonomists (e.g. Antonio Negri, Mario Tronti), the French ultra-left (e.g. Échanges et Mouvement); and within anarchism (especially Bob Black and the post-left anarchy tendency).

Stir crazy is a phrase that dates to 1908 according to the Oxford English Dictionary and the online Etymology Dictionary. Used among inmates in prison, it referred to a prisoner who became mentally unbalanced because of prolonged incarceration. The term "stir crazy" is based upon the slang "stir" (1851) to mean prison. It is now used to refer to anyone who becomes restless or anxious from feeling trapped and even somewhat claustrophobic in an environment perceived to be more static and unengaging than they can any longer continue to hold interest, meaning, and value to and for them.

"Stir crazy" could be classified as a more specific form of boredom, but combined with elevated and often increasing levels of anxiety, frustration, agitation, fidgeting, bipolar type mood swings, and accessory episodes of acting out impulsively or otherwise antisocially on those feelings, the longer the unengaging non-stimulating environment is persisted in.

Islamophobia in the United Kingdom refers to a set of discourses, behaviours and structures which express feelings of anxiety, fear, hostility and rejection towards Islam and/or Muslims in the United Kingdom. Islamophobia can manifest itself through discrimination in the workforce, negative coverage in the media, and violence against Muslims.

As of 2017, acid attacks, arson attacks against mosques and vehicle ramming have statistically risen against Muslims, predominately in England and Scotland.

Zymotic disease was a 19th-century medical term for acute infectious diseases, especially "chief fevers and contagious diseases (e.g. typhus and typhoid fevers, smallpox, scarlet fever, measles, erysipelas, cholera, whooping-cough, diphtheria, &c.)".

Zyme or microzyme was the name of the organism presumed to be the cause of the disease.

As originally employed by Dr W. Farr, of the British Registrar-General's department, the term included the diseases which were "epidemic, endemic and contagious," and were regarded as owing their origin to the presence of a morbific principle in the system, acting in a manner analogous to, although not identical with, the process of fermentation.

In the late 19th century, Antoine Béchamp proposed that tiny organisms he termed "microzymas", and not cells, are the fundamental building block of life. Bechamp claimed these microzymas are present in all things—animal, vegetable, and mineral—whether living or dead . Microzymas are what coalesce to form blood clots and bacteria. Depending upon the condition of the host, microzymas assume various forms. In a diseased body, the microzymas become pathological bacteria and viruses. In a healthy body, microzymas form healthy cells. When a plant or animal dies, the microzymas live on. His ideas did not gain acceptance.

The word "zymotic" comes from the Greek word ζυμοῦν "zumoûn" which means "to ferment". It was in British official use from 1839. This term was used extensively in the English Bills of Mortality as a cause of death from 1842. Robert Newstead (1859–1947) used this term in a 1908 publication in the "Annals of Tropical Medicine and Parasitology", to describe the contribution of house flies ("Musca domestica") towards the spread of infectious diseases. However, by the early 1900s, bacteriology "displaced the old fermentation theory", and so the term became obsolete.

In her "Diagram of the causes of mortality in the army in the East", Florence Nightingale depicts The blue wedges measured from the centre of the circle represent area for area the deaths from Preventible or Mitigable Zymotic diseases ; the red wedges measured from the centre the deaths from wounds, & the black wedges measured from the centre the deaths from all other causes.

Melancholia (from , '), also lugubriousness, from the Latin "lugere", to mourn; moroseness, from the Latin "morosus", self-willed, fastidious habit; wistfulness, from old English "wist": intent, or saturnine, was a concept in ancient and pre-modern medicine. Melancholy was one of the four temperaments matching the four humours. In the 19th century, "melancholia" could be physical as well as mental, and melancholic conditions were classified as such by their common cause rather than by their properties.

In addition to celibacy, the theory cites declining numbers of marriages and declining birthrates in Japan. According to surveys conducted by the Japan Association for Sex Education, between 2011 and 2013, the number of female college students reporting to be virgins increased. Additionally, surveys conducted by the Japanese Family Planning Association (JFPA) indicated a high number of Japanese women who reported that they "were not interested in or despised sexual contact". Meanwhile, surveys conducted by the National Institute of Population and Social Security Research in Japan in 2008 and 2013, revealed that the number of Japanese men and women reporting to not be in any kind of romantic relationship grew by 10%.

The theory attributes two possible causes for these reports: the past two decades of economic stagnation as well as high gender inequality in Japan.

Katagelasticism is a psychological condition in which a person excessively enjoys laughing at others (coined by Christian F. Hempelmann and Sean Harrigan from ("katagelastēs"), Ancient Greek for “mocker”). Katagelasticists actively seek and establish situations in which they can laugh at others (at the expense of these people). There is a broad variety of things that katagelasticists would do—starting from harmless pranks or word plays to truly embarrassing and even harmful, mean-spirited jokes. They would be of the opinion that laughing at others is part of the daily life and if others do not like being laughed at, they should just fight back. For the katagelasticists it is fun laughing at others and there is almost nothing that might hinder them from doing so. For them, some people even might provoke getting laughed at (and surely deserve being laughed at). This condition often makes it difficult for sufferers to gain and maintain acquaintances and romantic partners.

Shortness of breath is the primary reason 3.5% of people present to the emergency department in the United States. Of these individuals, approximately 51% are admitted to the hospital and 13% are dead within a year. Some studies have suggested that up to 27% of people suffer from dyspnea, while in dying patients 75% will experience it. Acute shortness of breath is the most common reason people requiring palliative care visit an emergency department.

Shortness of breath, also known as dyspnea, is a feeling like one cannot breathe well enough. The American Thoracic Society defines it as "a subjective experience of breathing discomfort that consists of qualitatively distinct sensations that vary in intensity", and recommends evaluating dyspnea by assessing the intensity of the distinct sensations, the degree of distress involved, and its burden or impact on activities of daily living. Distinct sensations include effort/work, chest tightness, and air hunger (the feeling of not enough oxygen).

Dyspnea is a normal symptom of heavy exertion but becomes pathological if it occurs in unexpected situations or light exertion. In 85% of cases it is due to asthma, pneumonia, cardiac ischemia, interstitial lung disease, congestive heart failure, chronic obstructive pulmonary disease, or causes, such as panic disorder and anxiety. Treatment typically depends on the underlying cause.

The practice is associated with significant health risks, as tongues are coated with a film of microorganisms, which may cause infections in the eye, such as conjunctivitis, herpes and chlamydia. It also carries the risk of corneal abrasion and corneal ulcers. Oral bacteria on the tongue can potentially enter corneal scratches caused by licking the eye, which then lead to infection.

Furthermore, there is also the risk of blindness from the resulting infections, as well as styes. The difference in bacteria between the eye and mouth is why it is no longer recommended to lick contact lenses before they are inserted into one's eye.