There have not been sufficient studies conducted to make conclusive statements about prevalence nor who tends to suffer EHS. One study found that 13.5% of a sample of undergrads reported at least one episode over the course of their lives, with higher rates in those also suffering from sleep paralysis.

As of 2014, no clinical trials had been conducted to determine what treatments are safe and effective; a few case reports had been published describing treatment of small numbers of people (two to twelve per report) with clomipramine, flunarizine, nifedipine, topiramate, carbamazepine, methylphenidate. Studies suggest that education and reassurance can reduce the frequency of EHS episodes. There is some evidence that individuals with EHS rarely report episodes to medical professionals.

Most blinded conscious provocation studies have failed to show a correlation between exposure and symptoms, leading to the suggestion that psychological mechanisms play a role in causing or exacerbating EHS symptoms. In 2010, Rubin et al. published a follow-up to their 2005 review, bringing the totals to 46 double-blind experiments and 1175 individuals with self-diagnosed hypersensitivity. Both reviews found no robust evidence to support the hypothesis that electromagnetic exposure causes EHS, as have other studies. They also concluded that the studies supported the role of the nocebo effect in triggering acute symptoms in those with EHS.

Some other types of studies suggest evidence for symptoms at non-thermal levels of electromagnetic exposure. A review in 2010 of ten studies on neurobehavioral and cancer outcomes near cell phone base stations found eight with increased prevalence, including sleep disturbance and headaches. Since 1962, the microwave auditory effect or tinnitus has been shown from radio frequency exposure at levels below significant heating. Studies during the 1960s in Europe and Russia claimed to show effects on humans, especially the nervous system, from low energy RF radiation; the studies were disputed at the time.

Other studies on sensitivity have looked at therapeutic procedures using non-thermal electromagnetic exposure, genetic factors, an alteration in mast cells, oxidative stress, protein expression and voltage-gated calcium channels. Mercury release from dental amalgam and heavy metal toxicity have also been implicated in exposure effects and symptoms. Another line of study has been the nature of hyper-sensitivity or intolerance and the range of environmental exposures which may be related to it. Some 80% of people with self-diagnosed electromagnetic intolerance also claim intolerance to low levels of chemical exposure.

Electromagnetic hypersensitivity (EHS) is a claimed sensitivity to electromagnetic fields, to which negative symptoms are attributed. EHS has no scientific basis and is not a recognised medical diagnosis. Claims are characterized by a "variety of non-specific symptoms, which afflicted individuals attribute to exposure to electromagnetic fields".

Those who are self-described with EHS report adverse reactions to electromagnetic fields at intensities well below the maximum levels permitted by international radiation safety standards. The majority of provocation trials to date have found that such claimants are unable to distinguish between exposure and non-exposure to electromagnetic fields. A systematic review in 2005 showed no convincing scientific evidence for symptoms being caused by electromagnetic fields. Since then, several double-blind experiments have shown that people who report electromagnetic hypersensitivity are unable to detect the presence of electromagnetic fields and are as likely to report ill health following a sham exposure as they are following exposure to genuine electromagnetic fields, suggesting the cause in these cases to be the nocebo effect.

A 2005 review by the UK Health Protection Agency and a 2006 systematic review each evaluated the evidence for various medical, psychological, behavioral, and alternative treatments for EHS and each found that the evidence-base was limited and not generalizable, but that the best evidence favored cognitive behavioural therapy. As of 2005, WHO recommended that people presenting with claims of EHS be evaluated to determine if they have a medical condition that may be causing the symptoms the person is attributing to EHS, that they have a psychological evaluation, and that the person's environment be evaluated for issues like air or noise pollution that may be causing problems.

Some people who feel they are sensitive to electromagnetic fields may seek to reduce their exposure or use alternative medicine. Government agencies have enforced false advertising claims against companies selling devices to shield against EM radiation.