Capillaritis is where the capillaries, usually of the legs or lungs, are inflamed.

It may occur in the lungs as pulmonary capillaritis, or in the skin as pigmented purpuric dermatosis.

On the legs it starts out as little brownish dots and can cause aching. Mild capillaritis clears up within 3–4 months.

Schamberg's disease is caused by leaky blood vessels near the surface of the skin, capillaries, which allow red blood cells to slip through into the skin. The red blood cells in the skin then fall apart and release their iron, which is released from hemoglobin. The iron causes a rust color and this accounts for the orange tint of the rash that can be seen on the skin. The underlying cause of the leaky blood vessels is not known, but researchers are suggesting that there could be some potential triggers. Some possible triggers include viral infection, a hypersensitivity to some agent, and interaction of some medications, such as thiamine and aspirin. Even though there is no correlation with genetics, there have been a few cases where few people in a family had this condition.

Although the cause of capillary inflammation is unknown, certain preventive measures can be taken. Doctors may prescribe medications that enhance the circulation of blood, which can keep blood vessels strong and healthy. Daily intake of vitamin C has proven to be a natural home remedy that can prevent the onsite of any disease or infection. Doctors always recommend that their patients monitor what they eat because their diet could be a possible factor that contributes to this condition. A healthy body that receives nutritious meals is more likely to have a healthy life that does not revolve around a lot of health problems.

Schamberg's disease is a skin disorder that causes a discoloration of the lower extremities. It manifests in the lower extremities and it gradually moves up towards anywhere on the body. This condition is caused by leaky blood vessels near the surface of the skin. The cause of the leaky capillaries is still unknown, but it is responsible for the discoloration of the skin. Since the blood vessels are weakened, red blood cells escape the blood vessels, where they end up near the surface of the skin. In one red blood cell, there are four heme groups and each heme group consists of one iron. Iron is responsible for helping red blood cells transfer oxygen from the lungs to the cells and carry carbon dioxide from the cells to the lungs. When red blood cells escape the blood vessels, red blood cells break apart, releasing hemoglobin. Iron is released from hemoglobin and is deposited into the skin. Since iron has no where to go and cannot be reabsorbed back into the blood, it will break apart. The iron complex hemosiderin is responsible for the discoloration of the skin, which creates patches of orange and brown pigmentation.