There is no universal cure for genophobia. Some ways of coping with or treating anxiety issues is to see a psychiatrist, psychologist, or licensed counselor for therapy. Some people experiencing pain during sex may visit their doctor or gynecologist. Medicine may also be prescribed to treat the anxiety brought on by the phobia.

Nosophobia is the irrational fear of contracting a disease, a type of specific phobia. Primary fears of this kind are fear of contracting HIV, pulmonary tuberculosis, venereal diseases, cancer, and heart diseases.

Some authors have suggested that the medical students' disease should accurately be referred to as "nosophobia" rather than "hypochondriasis", because the quoted studies show a very low percentage of hypochondriacal character of the condition.

The word "nosophobia" comes from the Greek νόσος "nosos" for "disease".

Genophobia or coitophobia is the physical or psychological fear of sexual relations or sexual intercourse. The word comes from the Greek nouns γένος "genos", meaning "offspring," and φόβος "phobos", meaning "fear." This word is also formed from the Greek noun "phobos" and the term coitus, referring to the act of copulation in which a male reproductive organ penetrates a female reproductive tract. The term erotophobia can also be used when describing genophobia. It comes from the name of the Greek god of erotic love, Eros. Genophobia can induce panic and fear in individuals, much like panic attacks. People who suffer from the phobia can be intensely affected by attempted sexual contact or just the thought of it. The extreme fear can lead to trouble in romantic relationships. Those afflicted by genophobia may stay away from getting involved in relationships to avoid the possibility of intimacy. This can lead to feelings of loneliness. Genophobic people may also feel lonely because they may feel embarrassed or ashamed of their personal fears.

In China, traditional treatment based on the causes suggested by cultural beliefs are administrated to the patient. Praying to gods and asking Taoist priests to perform exorcism is common. If a fox spirit is believed to be involved, people may hit gongs or beat the person to drive it out. The person will receive a yang- or yin-augmenting Chinese medicine potion, usually including herbs, pilose antler (stag of deer) or deer tail, and tiger penis, deer penis, or fur seal penis. Other foods for therapy are pepper soup, ginger soup and liquor.

In historical culture-bound cases, reassurance and talks on sexual anatomy are given. Patients are treated with psychotherapy distributed according to symptoms and to etiologically significant points in the past. Prognosis appears to be better in cases with a previously functional personality, a short history and low frequency of attacks, and a relatively uncomplicated sexual life.

For sporadic Western cases, careful diagnostic workup including searching for underlying sexual conflict is common. The choice of psychotherapeutic treatment is based on the psychiatric pathology found.