Anti-anxiety and antidepressant medication is commonly prescribed for treatment of social anxiety disorder. Selective serotonin reuptake inhibitors (SSRIs) such as sertraline, fluvoxamine and paroxetine are common medications which alleviate social phobia successfully in the short term but it is not certain if they are useful in the long-term. Also the MAOI moclobemide works well on treating social phobia in the short term. Patients who have avoided certain situations should make a big effort to become exposed to these situations while at the same time taking antidepressant medication. Anxiolytic medication aids a patient to handle social or professional situations before more lasting treatment has had an effect and therefore it is a provider of short term relief, but anxiolytics have a risk of dependence. Beta-adrenergic antagonists help to control palpitations and tremors unresponsive to the treatment of anxiolytic medication. One must read the precautions of these drugs outlined in the manufacturer's literature and be careful to watch out for the contraindications of these drugs.

Cognitive behavioral therapy (CBT) is commonly used to treat social phobia.

Phobias of this sort can usually be treated by different types of therapies, including: cognitive behavioral therapy (CBT), psychotherapy, behavior therapy and exposure therapy.

Practice may play an important part in overcoming fear. It may be helpful to sufferers to increase phone usage at a slow pace, starting with simple calls and gradually working their way up. For example, they may find it easier to start with automated calls, move on to conversations with family and friends, and then further extend both the length of conversations and the range of people with whom conversations are held.

Coping strategies may consist of planning the conversation ahead of time and rehearsing, writing or noting down what needs to be said. This may be helped by having privacy in which to make a call.

Associated avoidance behavior may include asking others (e.g. relatives at home) to take phone calls and exclusively using answering machines. The rise in the use of electronic text-based communication (the Internet, email and text messaging) has given many sufferers alternative means of communication that they tend to find considerably less stressful than the phone. However, some individuals experience "textphobia", a fear or anxiety of texting or messaging, and also avoid those forms of communication.

Sufferers may find it helpful to explain the nature of the phobia to friends, so that a failure to respond to messages is not misinterpreted as rudeness or an unwillingness to communicate.

Training courses in public speaking and/or organizations such as Australian Rostrum, Toastmasters International, POWERtalk International, and Association of Speakers Clubs can help people to reduce their fear of public speaking to manageable levels. Self-help materials that address public speaking are among the best selling self-help topics. To temporarily treat their phobia, some affected people have turned to certain types of medications, typically beta blockers.

In some cases, anxiety can be mitigated by a speaker not attempting to resist their anxiety, thus fortifying the anxiety/fight-or-flight loop. Other strategies involve using one's nervousness to enliven an otherwise fearful speech presentation.

A speaker's anxiety can also be reduced if they know their topic well and believe in it. It has been suggested that people should practice speaking in front of smaller, less intimidating groups when they're getting started in public speaking. Additionally, focusing on friendly, attentive people in the audience has been found to help.

Traditional advice has been to urge fearful speakers not to take themselves too seriously, and to be reminded that mistakes are often unnoticed by audiences. Gaining experience in public speaking often results in it becoming less anxiety-provoking over time. Recent studies suggest that there is a close link between fear of public speaking and self-efficacy and that attempts to help presenters improve their self-efficacy will also reduce this fear.

Loosening up a "tough crowd" by asking questions promotes audience participation. A speaker may also find this exercise to be helpful when their mind "goes blank", as it gives them time to regain their train of thought.

Many people report stress-induced speech disorders which are only present during public speech. Some individuals with glossophobia have been able to dance, perform in public, or even to speak (such as in a play), or sing if they cannot see the audience, or if they feel that they are presenting a character or stage persona other than themselves. Being able to blend in a group (as in a choir or band) has been reported to also alleviate some anxiety caused by glossophobia.

It has been estimated that 75% of all people experience some degree of anxiety/nervousness when it comes to public speaking. In fact, surveys have shown that most people fear public speaking more than they fear death. If untreated, public speaking anxiety can lead to serious detrimental effects on one's quality of life, career goals and other areas. For example, educational goals requiring public speaking might be left unaccomplished. However, not all persons with public speaking anxiety are necessarily unable to achieve work goals, though this disorder becomes problematic when it prevents an individual from attaining or pursuing a goal they might otherwise have - were it not for their anxiety.

A recent study conducted by Garcia-Lopez, Diez-Bedmar, and Almansa-Moreno (2013) has reported that previously trained students could act as trainers to other students and help them to improve their public speaking skills.