There is no universal cure for genophobia. Some ways of coping with or treating anxiety issues is to see a psychiatrist, psychologist, or licensed counselor for therapy. Some people experiencing pain during sex may visit their doctor or gynecologist. Medicine may also be prescribed to treat the anxiety brought on by the phobia.

Erotophobia is a term coined by a number of researchers in the late 1970s and early 1980s to describe one pole on a continuum of attitudes and beliefs about sexuality. The model of the continuum is a basic polarized line, with erotophobia (fear of sex or negative attitudes about sex) at one end and erotophilia (positive feelings or attitudes about sex) at the other end.

The word erotophobia is derived from the name of Eros, the Greek god of erotic love, and Phobos, Greek (φόβος) for "fear".

Erotophobia has many manifestations. An individual or culture can have one or multiple erotophobic attitudes. Some types of erotophobia include fear of nudity, fear of sexual images, homophobia, fear of sex education, fear of sexual discourse.

Genophobia or coitophobia is the physical or psychological fear of sexual relations or sexual intercourse. The word comes from the Greek nouns γένος "genos", meaning "offspring," and φόβος "phobos", meaning "fear." This word is also formed from the Greek noun "phobos" and the term coitus, referring to the act of copulation in which a male reproductive organ penetrates a female reproductive tract. The term erotophobia can also be used when describing genophobia. It comes from the name of the Greek god of erotic love, Eros. Genophobia can induce panic and fear in individuals, much like panic attacks. People who suffer from the phobia can be intensely affected by attempted sexual contact or just the thought of it. The extreme fear can lead to trouble in romantic relationships. Those afflicted by genophobia may stay away from getting involved in relationships to avoid the possibility of intimacy. This can lead to feelings of loneliness. Genophobic people may also feel lonely because they may feel embarrassed or ashamed of their personal fears.

A term whose meaning is synonymous with eurotophobia is kolpophobia; however; the scope of kolpophobia can sometimes be broader, allowing for the inclusion of all sex organs. Although eurotophobia does not have an interlingual classical compound, kolpophobia has a Greek etymological derivation with the prefix "kolpo" meaning a fold that usually alludes to the vulva. Eurotophobia is a hyponym of genitophobia. On the other hand, the term vaginaphobia is used to denote fear of female genitals in the context of sexual orientation. The male counterpart that analogously corresponds with this condition is called phallophobia.

Such an exhibit of detestation for the female genitalia can originate from some innate inherency, or learned from frequent denunciations of one's aesthetic appearance and aberrating comments during childhood. Sometimes eurotophobia is a spin-off of aversion to perceived by-products of the female genitalia, such as discharge or mucus. The condition can manifest itself in both men and women and is at times triggered by some strenuous event. This phenomenon has also been observed in medical students, particularly those in the field of obstetrics, at times leading to dropping out. According to the online Romanian women's magazine Ele, the appropriation of this condition by women may lead to various symptoms including depression and self-harm and that it originates from a highly prudish and puritanical upbringing. Other explanations posit the transmission of urban legends such as vagina dentata or Freudian concepts such as castration anxiety. Eurotophobes may also have developed their condition after being molested by an adult female.