Exposure therapy has been proven as an effective treatment for people who have a fear of bees. It is recommended that people place themselves in a comfortable open environment, such as a park or garden, and gradually over a prolonged period of time move closer to the bees. This process should not be rushed, it may take many months spent watching bees before people feel comfortable in their presence.

Apiphobia is one of the zoophobias prevalent in young children and may prevent them from taking part in any outdoor activities. Older people control the natural fear of bees more easily. However, some adults face hardships of controlling the fear of bees.

A recommended way of overcoming child's fear of bees is training to face fears (a common approach for treating specific phobias). Programs vary.

Fear of bees (or of bee stings), technically known as melissophobia (from , "melissa", "honey bee" + , "phobos", "fear") and occasionally misspelled as melissaphobia and also known as apiphobia (from Latin "apis" for "honey bee" + "", "phobos", "fear"), is one of the common fears among people and is a kind of specific phobia.

Most people have been stung by a bee or had friends or family members stung. A child may fall victim by treading on a bee while playing outside. The sting can be quite painful and in some individuals results in swelling which may last for several days, and can also provoke allergic reactions such as anaphylaxis, so the development of loathsome fear of bees is quite natural.

Ordinary (non-phobic) fear of bees in adults is generally associated with lack of knowledge. The general public is not aware that bees attack in defense of their hive, or when accidentally squashed, and an occasional bee in a field presents no danger. Moreover, the majority of insect stings in the United States are attributed to yellowjacket wasps, which are often mistaken for a honeybee.

Unreasonable fear of bees in humans may also have a detrimental effect on ecology. Bees are important pollinators, and when, in their fear, people destroy wild colonies of bees, they contribute to environmental damage and may also be the cause of the disappearing bees.

The renting of bee colonies for pollination of crops is the primary source of income for beekeepers in the US, but as the fears of bees spread, it becomes hard to find a location for the colonies because of the growing objections of local population.

Zoophobia or animal phobia is a class of specific phobias to particular animals, or an irrational fear or even simply dislike of any non-human animals.

Examples of specific zoophobias would be entomophobias, such as that of bees (apiphobia). Fears of spiders (arachnophobia), birds (ornithophobia) and snakes (ophidiophobia) are also common. See the article at -phobia for the list of various phobias. Sigmund Freud mentioned that an animal phobia is one of the most frequent psychoneurotic diseases among children.

Zoophobia is not the sensible fear of dangerous or threatening animals, such as wild dogs (example: wolves, dingoes, and coyotes), big cats, bears or venomous snakes. It is a phobia of animals that causes distress or dysfunction in the individual's everyday life.

Entomophobia (also known as insectophobia) is a specific phobia characterized by an excessive or unrealistic fear of one or more classes of insect, and classified as a phobia by the DSM-5. More specific cases included apiphobia (fear of bees) and myrmecophobia (fear of ants). One book claims 6% of all US inhabitants suffer from it.

Entomophobia may develop after the person has had a traumatic experience with the insect(s) in question. It may develop early or later in life and is quite common among the animal phobias. Typically one suffers from a fear from one specific type of insect, and entomophobia leads to behavioral changes: the sufferer will avoid situations where they may encounter the specific type of insect. Cognitive behavioral therapy is considered an effective treatment.