There are many ways to treat ailurophobia; treatment is usually carried out by a psychiatrist or other therapy specialist.

One strongly motivated patient was able to recover by slowly becoming accustomed to cat fur by first touching varying types of velvet, then becoming accustomed to a toy kitten, and finally a live kitten which the patient subsequently adopted.

The phobia manifests itself in different ways. For most people it is less about fear than about loathing, similar to the reaction many people have to snakes or rats. Some people experience it almost all the time, others just in response to direct stimuli. Some possible situations that can trigger the loathing of cats are: hearing purring, seeing a cat in real life, imagining the possibility of a cat touching or rubbing against one, the thought of meeting a cat in the dark, seeing the staring eyes of a cat (cats have the tendency to stare at passers-by) cats in pictures and on television, and cat-like toys and cat-like fur. Big cats such as lions or tigers can also trigger the stimuli associated with a phobia.