A study published in the journal "Computers in Human Behavior" was conducted between 1992 and 1994 surveying first-year college students across various countries. The overall percentage of the 3,392 students who responded with high-level technophobic fears was 29%. In comparison, Japan had 58% high-level technophobes, India had 82%, and Mexico had 53%.

A published report in 2000 stated that roughly 85 to 90 percent of new employees at an organization may be uncomfortable with new technology, and are technophobic to some degree.

Technophobia (from Greek τέχνη "technē", "art, skill, craft" and φόβος "phobos", "fear") is the fear or dislike of advanced technology or complex devices, especially computers. Although there are numerous interpretations of technophobia, they seem to become more complex as technology continues to evolve. The term is generally used in the sense of an irrational fear, but others contend fears are justified. It is related to cyberphobia and is the opposite of technophilia. Dr. Larry Rosen, research psychologist, computer educator, and professor at the California State University suggests that there are three dominant subcategories of technophobes- the "uncomfortable users", the "cognitive computerphobes", and "anxious computerphobes". First receiving widespread notice during the Industrial Revolution, technophobia has been observed to affect various societies and communities throughout the world. This has caused some groups to take stances against some modern technological developments in order to preserve their ideologies. In some of these cases, the new technologies conflict with established beliefs, such as the personal values of simplicity and modest lifestyles. Examples of technophobic ideas can be found in multiple forms of art, ranging from literary works such as "Frankenstein" to films like "Metropolis". Many of these works portray the darker side of technology as perceived by the technophobic. As technologies become increasingly complex and difficult to understand, people are more likely to harbor anxieties relating to their use of modern technologies.

Digital phobic is an informal phrase used to describe a reluctance to become fully immersed in the digital age for being fearful of how it might negatively change or alter everyday life.

The fast-paced development of the digital world in the twenty-first century has contributed to the digital divide becoming a very real problem for a segment of the population for whom a lack of education of, interest in, or access to digital devices has left them excluded from the technological world and fearful of its growing omnipresence.

Digital phobic is part of a growing dictionary of digital vocabulary exploring the social impact of the technological age. The phrase considers the fears associated with technological evolution and change, and acknowledges the possibility of exclusion as a result of a rising reliance on technology in day-to-day life.

Cyberphobia is a concept introduced in 1980, described as a specific phobia expressed as "an irrational fear of or aversion to computers" or more generally, a fear and/or inability to learn about new technologies.

Some forms of cyberphobia may range from the more passive forms of technophobia of those who are indifferent toward cyberspace to the responses of those who see digital technology as a medium of intrusive surveillance; more extreme responses may involve anti-technological paranoia expressed by social movements that radically oppose ‘technological society’ and ‘the New World Order’.

There are different ways that someone could experience cyberphobia. Teachers may experience a form of cyberphobia if they are forced to change their way of teaching. Another way people may experience cyberphobia is if they feel that they are incompetent, or that the new technology is not needed to advance in life, or that they feel that they lack skills for the new age of technology. Another way people may experience cyberphobia is if they feel like they are going to lose control, or the new technology will affect their status in life.

Research shows that opposition to attitudinal change can gradually give way to acceptance with the passage of time. Attitudinal change towards acceptance may be a slow and even tedious experience for some teachers.

Digital phobia has had a negative impact on the field of education. Some teachers have expressed a fear that new and advanced technology is supplanting them as the masters of their fields of study and a study of teachers in Wilmington, Delaware has shown that educators in this area are acclimating to the new technology in their classrooms at a slower pace. The local researchers believe that there are many factors why that is the case and some of the things they have found are things such as a lack of technological education by the teachers, and also the lack of time, or incentive to adjust to the new technology. University Larry Cuban has stated that "The introduction of computers into school was supposed to improve academic achievement , and alter how teachers taught. Neither has occurred."

The constant infusion of new technology has many teachers fearing that they are losing their classroom. This new technology is essentially diminishing the role of a teacher in the classroom.

Researchers believe that educators are slow to adapt to technology because they aren't given time to acclimate to the new technology, causing them to hesitate to use it in the classroom and express fear that these technologies may interfere with genuine learning particularly in humanities and creative subjects. In an article for the "New Media Reader," Theodor H. Nelson wrote that people are opposed to the computer because they believe it is "cold" and "inhuman", but a human can be just as inhuman and maybe even more so than the actual machine itself.

In various studies, about one half of the patients who seek medical treatment for symptoms of MCS meet the criteria for depressive and anxiety disorders. Because many people eliminate whole categories of food in an effort to reduce symptoms, a complete review of the patient's diet may be needed to avoid nutritional deficiencies.

Genetic differences relating to toxicant metabolism pathways, such as polymorphisms and differences in expression in CYP2D6, NAT2, GSTM1, and PON1 and PON2, have been proposed as a cause for differences in susceptibility to MCS. Elevated nitric oxide and peroxynitrite (NO/ONOO-) could then cause the symptoms of MCS and several related conditions, including fibromyalgia, posttraumatic stress disorder, Gulf War syndrome, and chronic fatigue syndrome.