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The cause of the outbreak was determined to be the addition of excessive doses of copper sulfate to the water supply of Solomon Dam to target a cyanobacteria bloom of "Cylindrospermopsis raciborskii". The excessive dosing was following the use of least-cost contractors to control the algae, who were unqualified in the field.
Toxins from the cyanobacteria itself had also been described as a possible cause.
Early suggestions included Toxocariasis.
In 1979 an outbreak of hepatoenteritis, also known as the Palm Island mystery disease, was reported and described a hepatitis-like illness (associated in many cases with dehydration and bloody diarrhoea) in 148 people (138 children and 10 adults) of Aboriginal and Torres Strait Islander descent in Palm Island, Queensland.
The presence of avian botulism is extremely hard to detect before an outbreak. Frequent surveillance of sites at risk is needed for early detection of the disease in order to take action and remove carcasses. Vaccines are also developed, but they are expected to have limited effectiveness in stemming outbreaks in wild waterbird populations. However may be effective in reducing mortality for endangered island waterfowl and small non-migratory wild populations. Field tests are needed.
Coconut cadang-cadang disease has no treatment yet. However, chemotherapy with antibiotics has been tried with tetracycline solutions; antibiotics failed trying to alter progress of the disease since they had no significant effect on any of the studied parameters. When the treated plants were at the early stage, tetracycline injections failed to prevent the progression of the palms to more advanced stages, nor did they affect significantly the mean number of spathes or nuts. Penicillin treatment had no apparent improvement either.
Control strategies are elimination of reservoir species, vector control, mild strain protection and breeding for host resistance. Eradication of diseased plants is usually performed to minimize spread but is of dubious efficacy due to the difficulties of early diagnosis as the virus etiology remains unknown and the one discovered are the three main stages in the disease development.
No definite control measures exist at the present.
- Genetic resistance and Vector control are not options because resistant/tolerant varieties have yet to be discovered, and there is no known vector of CCCVd.
- Eradication is ineffective because of the long latent period between infection and appearance of symptoms, which is approximately 1 to 2 years.
- Cross-protection (see also Influenza vaccine: Cross-protection) is a possibility for the future. Cross infection means inoculating the coconut with a mild strain of the viroid to give the coconut tree some degree of protection from infection by the killer form. This is similar to Edward Jenner's pioneering smallpox vaccine. He used cowpox to confer induced immunity on humans. But in the case of Cadang-cadang, this is still under research.
There is no known treatment for FTS, as the cause is not yet known. There are conflicting reports on whether the paralysis is reversible; some sources claim that moving an elephant away from the area in which it contracted the condition will allow it to recover, while others claim that damage to the trunk is irreversible.
In some extreme cases, wildlife managers have killed affected elephants for humane reasons.
Jembrana disease is an acute viral disease of cattle. While it produces relatively mild symptoms in taurine cattle, the Jembrana virus is particularly severe in Bali cattle where it has a fatality rate of approximately seventeen percent. Its first documented outbreak occurred in 1964 in the Jembrana district of Bali, Indonesia. Within two years of its appearance the disease had killed an estimated 26,000 of the approximately 300,000 cattle on Bali Island. The virus belongs to the Lentivirus genus, which include immunodeficiency viruses such as HIV. Instead of the chronic disease produced by most Lentivruses, Jembrana disease produces acute effects. After an incubation period of 5–12 days the disease produces symptoms including loss of appetite, fever, lethargy, enlargement of the lymph nodes, and diarrhea. There is at least one strain that has been sequenced.
During the latest outbreak of the disease (2004), several treatment methods were tested. Main treatment involved the administration of antibiotics, in some cases glucose solution or dietary mixtures were additionally supplemented. Outcome of the different treatment methods varied greatly. Especially the success of antibiotic treatment and a widespread use on wild animals remains a matter of debate.
Coxsackie B virus is spread by contact and epidemics usually occur during warm weather in temperate regions and at any time in the tropics.
The botulinum neurotoxin is lethal because it causes paralysis. Field identification involves locating birds showing flaccidity in the legs, wings and neck, as well as the presence of protuberant nictitating membrane. The presence of several dozen, or even hundreds, of fresh waterbird carcasses is the stereotypical sign an outbreak has occurred. In this case the specimens need to be taken to disease laboratory to determine the cause of mortality. Most commonly, detection of "C. botulinum" in carcasses during lab work is accomplished through analysis of polymerase chain reactions (PCR) and is often the most successful method.
The illness lasts about a week and is rarely fatal. Treatment includes the administration of nonsteroidal anti-inflammatory agents or the application of heat to the affected muscles. Relapses during the weeks following the initial episode are a characteristic feature of this disease.
Copper and copper alloys such as brass have been found to be toxic to bacteria via the oligodynamic effect. The exact mechanism of action is unknown, but common to other heavy metals. Viruses are less susceptible to this effect than bacteria. Associated applications include the use of brass doorknobs in hospitals, which have been found to self-disinfect after eight hours, and mineral sanitizers, in which copper can act as an algicide. Overuse of copper sulfate as an algicide has been speculated to have caused a copper poisoning epidemic on Great Palm Island in 1979.
Treatment of asymptomatic carriers should be considered if parasites are still detected after 3 months. In mild-to-moderate babesiosis, the treatment of choice is a combination of atovaquone and azithromycin. This regimen is preferred to clindamycin and quinine because side effects are fewer. The standard course is 7 to 10 days, but this is extended to at least 6 weeks in people with relapsing disease. Even mild cases are recommended to be treated to decrease the chance of inadvertently transmitting the infection by donating blood. In life-threatening cases, exchange transfusion is performed. In this procedure, the infected red blood cells are removed and replaced with uninfected ones.
Imizol is a drug used for treatment of babesiosis in dogs.
Extracts of the poisonous, bulbous plant "Boophone disticha" are used in the folk medicine of South Africa to treat equine babesiosis. "B. disticha" is a member of the daffodil family Amaryllidaceae and has also been used in preparations employed as arrow poisons, hallucinogens, and in embalming. The plant is rich in alkaloids, some of which display an action similar to that of scopolamine.
Too much copper in water may damage marine and freshwater organisms such as fish and molluscs. Fish species vary in their sensitivity to copper, with the LD50 for 96-h exposure to copper sulphate reported to be in the order of 58 mg per litre for Tilapia ("Oreochromis niloticus") and 70 mg per litre for catfish ("Clarias gariepinus") The chronic effect of sublethal concentrations of copper on fish and other creatures is damage to gills, liver, kidneys and the nervous system. It also interferes with the sense of smell in fish, thus preventing them from choosing good mates or finding their way to mating areas.
Copper-based paint is a common marine antifouling agent. In the United States, copper-based paint replaced tributyltin, which was banned due to its toxicity, as a way for boats to control organic growth on their hulls. In 2011, Washington state became the first U.S. state to ban the use of copper-based paint for boating, although it only applied to recreational boats. California has also pursued initiatives to reduce the effect of copper leaching, with the U.S. EPA pursuing research.
Diphtheritic stomatitis is a recently discovered disease and has thus far been reported only in Yellow-eyed penguins ("Megadyptes antipodes"). Its symptoms are similar to human diphtheria and is characterized by infecteous lesions in the mouth area that impede swallowing and cause respiratory troubles. The infection is caused by "Corynebacterium amycolatum", an aerobic Gram-positive bacterium and mainly affects very young chicks. However, it seems likely that a triggering agent (e.g. a virus) might be involved in which renders the corynebacterium a secondary pathogen.
The disease has been a serious cause of mortality in the 2002 and 2004 Yellow-eyed penguin breeding seasons. It seems that only the New Zealand South Island and Stewart Island/Rakiura were affected.
The paralysis is caused by degeneration of peripheral nerves, which begins at the tip of the trunk.
A comparison of areas affected by FTS and unaffected areas suggests three plant species may be the cause: "Heliotropium", specifically "Heliotropium ovalifolium", "Indigofera", and "Boerhavia". Native to Nigeria, "Heliotropium ovalifolium" is known to be poisonous and has been cited to cause diarrhea and bleeding in humans. It is theorized that elephants are being forced to consume toxic vegetation due to changes in weather patterns and to the natural ecology of their habitats. Several cases were observed when drought conditions enabled elephants to access grasslands adjacent to Fothergill Island.
Lead poisoning has also been suggested as a cause. The degeneration of nerves found in afflicted elephants mirrors the effect of lead intoxication in humans and horses. Additionally, potentially mitigating factors of lead poisoning, such as dietary selenium, are deficient in Zimbabwe.
There is no vaccine for SARS to date. Isolation and quarantine remain the most effective means to prevent the spread of SARS. Other preventative measures include:
- Handwashing
- Disinfection of surfaces for fomites
- Wearing a surgical mask
- Avoiding contact with bodily fluids
- Washing the personal items of someone with SARS in hot, soapy water (eating utensils, dishes, bedding, etc.)
- Keeping children with symptoms home from school
Many public health interventions were taken to help control the spread of the disease; which is mainly spread through respiratory droplets in the air. These interventions included earlier detection of the disease, isolation of people who are infected, droplet and contact precautions, and the use of personal protective equipment (PPE); including masks and isolation gowns. A screening process was also put in place at airports to monitor air travel to and from affected countries. Although no cases have been identified since 2004, the CDC is still working to make federal and local rapid response guidelines and recommendations in the event of a reappearance of the virus.
Ichthyoallyeinotoxism, or hallucinogenic fish inebriation, comes from eating certain species of fish found in several parts of the tropics, the effects of which are reputed to be similar in some aspects to LSD. Experiences may include vivid auditory and visual hallucinations. This has given rise to the collective common name "dream fish" for ichthyoallyeinotoxic fish.
The species most commonly claimed to be capable of producing this kind of toxicity include several species from the "Kyphosus" genus, including "Kyphosus fuscus", "K. cinerascens" and "K. vaigiensis". It is unclear whether the toxins are produced by the fish themselves or by marine algae in their diet, but a dietary origin may be more likely.
"Sarpa salpa", a species of bream, can induce LSD-like hallucinations if it is eaten. These widely distributed coastal fish are called "the fish that make dreams" in Arabic. In 2006, two men who ate fish, apparently the "Sarpa salpa" caught in the Mediterranean were affected by ichthyoallyeinotoxism and experienced hallucinations lasting for several days.
Other hallucinogenic fish are "Siganus spinus", called "the fish that inebriates" in Reunion Island, and "Mulloides flavolineatus" (formerly "Mulloidichthys samoensis"), called "the chief of ghosts" in Hawaii.
Some hypotheses as to the cause of the disease include genetics, cycad seeds, and ingested beta-Methylamino-L-alanine (BMAA) from the consumption of fruit bats.
Babesiosis is a malaria-like parasitic disease caused by infection with "Babesia", a genus of Apicomplexa. Human babesiosis is an uncommon but emerging disease in the Northeastern and Midwestern United States and parts of Europe, and sporadic throughout the rest of the world. It occurs in warm weather. Ticks transmit the human strain of babesiosis, so it often presents with other tick-borne illnesses such as Lyme disease. After trypanosomes, "Babesia" is thought to be the second-most common blood parasite of mammals, and they can have a major impact on health of domestic animals in areas without severe winters. In cattle, a major host, the disease is known as Texas cattle fever, redwater, or piroplasmosis.
Flinders Island spotted fever is a condition characterized by a rash in approximately 85% of cases.
It is associated with "Rickettsia honei".
Taravana is a disease often found among Polynesian island natives who habitually dive deep without breathing apparatus many times in close succession, usually for food or pearls. These free-divers may make 40 to 60 dives a day, each of 30 or 40 metres (100 to 140 feet).
Taravana seems to be decompression sickness. The usual symptoms are vertigo, nausea, lethargy, paralysis and death. The word "taravana" is Tuamotu Polynesian for "to fall crazily".
Taravana is also used to describe someone who is "crazy because of the sea".
Lucio Godina (March 8, 1908 – November 24, 1936) and Simplicio Godina (March 8, 1908 - December 8, 1936) were pygopagus conjoined twins from the island of Samar in the Philippines.
At the age of 21 they married Natividad and Victorina Matos, who were identical twins. They performed in various sideshow acts, including in an orchestra on Coney Island and in dance with their wives.
After Lucio died of rheumatic fever in New York City, doctors operated to separate him from Simplicio. Simplicio survived the operation, but died shortly thereafter due to spinal meningitis.
Antibiotics are ineffective, as SARS is a viral disease. Treatment of SARS is largely supportive with antipyretics, supplemental oxygen and mechanical ventilation as needed.
People with SARS must be isolated, preferably in negative pressure rooms, with complete barrier nursing precautions taken for any necessary contact with these patients.
Some of the more serious damage caused by SARS may be due to the body's own immune system reacting in what is known as cytokine storm.
As of 2017, there is no cure or protective vaccine for SARS that has been shown to be both safe and effective in humans. The identification and development of novel vaccines and medicines to treat SARS is a priority for governments and public health agencies around the world. MassBiologics, a non-profit organization engaged in the discovery, development and manufacturing of biologic therapies, is cooperating with researchers at NIH and the CDC developed a monoclonal antibody therapy that demonstrated efficacy in animal models.
Avian malaria is a parasitic disease of birds, caused by parasite species belonging to the genera "Plasmodium" and "Hemoproteus" (phylum Apicomplexa, class Haemosporidia, family Plasmoiidae). The disease is transmitted by a dipteran vector including mosquitoes in the case of "Plasmodium" parasites and biting midges for "Hemoproteus." The range of symptoms and effects of the parasite on its bird hosts is very wide, from asymptomatic cases to drastic population declines due to the disease, as is the case of the Hawaiian honeycreepers. The diversity of parasites is large, as it is estimated that there are approximately as many parasites as there are species of hosts. Co-speciation and host switching events have contributed to the broad range of hosts that these parasites can infect, causing avian malaria to be a widespread global disease, found everywhere except Antarctica.