Selective serotonin reuptake inhibitors (SSRIs) are used, especially with exhibitionists, non-offending pedophiles, and compulsive masturbators. They are proposed to work by reducing sexual arousal, compulsivity, and depressive symptoms. However, supporting evidence for SSRIs is limited.

Pharmacological treatments can help people control their sexual behaviors, but do not change the content of the paraphilia. They are typically combined with cognitive behavioral therapy for best effect.

Psychosexual disorders can vary greatly in severity and treatability. Medical professionals and licensed therapists are necessary in diagnosis and treatment plans. Treatment can vary from therapy to prescription medication. Sex therapy, behavioral therapy, and group therapy may be helpful to those suffering distress from sexual dysfunction. More serious sexual perversions may be treated with androgen blockers or selective serotonin reuptake inhibitors (SSRIs) to help restore hormonal and neurochemical balances.

Transvestism is the practice of dressing and acting in a style or manner traditionally associated with the opposite sex. In some cultures, transvestism is practiced for religious, traditional or ceremonial reasons.

Biological treatments physically alter primary and secondary sex characteristics to reduce the discrepancy between an individual's physical body and gender identity. Biological treatments for GID without any form of psychotherapy is quite uncommon. Researchers have found that if individuals bypass psychotherapy in their GID treatment, they often feel lost and confused when their biological treatments are complete.

Psychotherapy, hormone replacement therapy, and sex reassignment surgery together can be effective treating GID when the WPATH standards of care are followed. The overall level of patient satisfaction with both psychological and biological treatments is very high.

Until the 1970s, psychotherapy was the primary treatment for gender dysphoria, and generally was directed to helping the person adjust to the gender of the physical characteristics present at birth. Psychotherapy is any therapeutic interaction that aims to treat a psychological problem. Though some clinicians still use only psychotherapy to treat gender dysphoria, it may now be used in addition to biological interventions. Psychotherapeutic treatment of GID involves helping the patient to adapt. Attempts to cure GID by changing the patient's gender identity to reflect birth characteristics have been ineffective.

Psychosexual disorder is a term which may simply refer to a sexual problem that is psychological, rather than physiological in origin. "Psychosexual disorder" was a term used in . The term of psychosexual disorder (Turkish: "Psikoseksüel bozukluk") used by the TAF for homosexuality as a reason to ban the LGBT people from military service.

Though coined as late as the 1910s, the phenomenon is not new. It was referred to in the Hebrew Bible. The word has undergone several changes of meaning since it was first coined and is still used in a variety of senses. Today, the term "transvestite" is commonly considered outdated and derogatory, with the term "cross-dresser" used as a more appropriate replacement. This is because the term "transvestite" was historically used to diagnose medical disorders, including mental health disorders, and transvestism was viewed as a disorder, but the term "cross-dresser" was coined by the transgender community. In some cases, however, the term "transvestite" is seen as more appropriate for use by members of the transgender community instead of by those outside of the transgender community, and some have reclaimed the word.

To determine relative prevalences of different fetishes, Italian researchers obtained an international sample of 5,000 individuals from 381 fetish-themed discussion groups. The relative prevalences were estimated based on (a) the number of groups devoted to a particular fetish, (b) the number of individuals participating in the groups and (c) the number of messages exchanged. Within the sample population (a population of adults online involved in sexual discussion), 12 percent indicated a fetish related to an "object associated with the body + external event" . This includes, but is not limited to, objects such as underwear, socks, shoes, etc. (see Table 1 in the .pdf of the first article cited).

Some people experience sexual excitement from the look or feel of a women's bra. The attraction may be to the look or feel of the material, such as lace, or how it looks on a person. Some people get excitement from removing a bra.

"Sex reassignment therapy" (SRT) is an umbrella term for all medical treatments related to sex reassignment of both transgender and intersex people.

Individuals make different choices regarding sex reassignment therapy, which may include female-to-male or male-to-female hormone replacement therapy (HRT) to modify secondary sex characteristics, sex reassignment surgery (such as orchiectomy) to alter primary sex characteristics, chest surgery such as top surgery or breast augmentation, or, in the case of trans women, a trachea shave, facial feminization surgery or permanent hair removal.

To obtain sex reassignment therapy, transsexual people are generally required to undergo a psychological evaluation and receive a diagnosis of gender identity disorder in accordance with the Standards of Care (SOC) as published by the World Professional Association for Transgender Health. This assessment is usually accompanied by counseling on issues of adjustment to the desired gender role, effects and risks of medical treatments, and sometimes also by psychological therapy. The SOC are intended as guidelines, not inflexible rules, and are intended to ensure that clients are properly informed and in sound psychological health, and to discourage people from transitioning based on unrealistic expectations.

Transsexual people experience a gender identity that is inconsistent with, or not culturally associated with, their assigned sex, and desire to permanently transition to the gender with which they identify, usually seeking medical assistance (including hormone replacement therapy and other sex reassignment therapies) to help them align their body with their identified sex or gender.

"Transsexual" is generally considered a subset of "transgender", but some transsexual people reject the label of "transgender". A medical diagnosis of gender dysphoria can be made if a person expresses a desire to live and be accepted as a member of their identified sex, and if a person experiences impaired functioning or distress as a result of their gender identity.

Dual-role transvestism is the formal diagnosis used by psychologists and physicians to describe people who wear clothes of the opposite sex to experience being the opposite sex temporarily, but don't have a sexual motive or want gender reassignment surgery. The International Classification of Diseases (ICD-10) list three diagnostic criteria for "Dual-role transvestism" (F64.1):

A person who is diagnosed with Dual-role transvestism should not receive a diagnosis of transvestic fetishism(F65.1),

Bondage pornography is the depiction of sexual bondage or other BDSM activities using photographs, stories, movies or drawings. Though often described as pornography, the genre involves the presentation of bondage fetishism or BDSM scenarios and does not necessarily involve the commonly understood pornographic styles. In fact, the genre is primarily interested with the presentation of a bondage scene and less with depictions of sexuality, such as nudity or sex scenes, which may be viewed as a distraction from the aesthetics and eroticism of the bondage scenario itself.

Historically, most subjects of bondage imagery have been women, and the genre has been criticized for promoting misogynistic attitudes and violence against women.

In the early 20th century, bondage imagery was available through "detective magazines", and comic books often featured characters being tied up or tying others up, particularly in "damsel in distress" plots.

There were also a number of dedicated fetish magazines which featured images of fetishism and bondage. The first of such magazines in the United States was "Bizarre", first published in 1946 by fetish photographer John Willie (the phallic pseudonym of John Coutts), who developed the concept in the 1920s. Willie was able to avoid controversy in censorship through careful attention to guidelines and the use of humor. Publication of "Bizarre" was suspended completely from 1947 to 1951 because of post-War paper shortages. By 1956 Willie was ready to give up the magazine, and in that year he sold it to someone described only as R.E.B., who published six more issues before "Bizarre" finally folded in 1959.

Willie is better remembered for his "Sweet Gwendoline" comic strips, in which Gwendoline is drawn as a rather naïve blonde "damsel in distress", with ample curves, who is unfortunate enough to find herself tied up in scene after scene by the raven-haired dominatrix and the mustachioed villain "Sir Dystic D'Arcy". She is rescued and also repeatedly tied up (though for benevolent reasons) by secret agent U-69 (censored to U89 in some editions). The comic strips were published largely in the 1950s and 60s. The story was published as a piecemeal serial, appearing usually two pages at a time in several different magazines over the years.

Though "Bizarre" was a small format magazine, it had a huge impact on later kink publications, such as ENEG's fetish magazine, "Exotique", published 1956-1959. "Exotique" was entirely devoted to fetish fashions and female-dominant bondage fantasies. The 36 issues featured photos and illustrations of dominatrix-inspired vamps (including Burtman's wife Tana Louise and iconic model Bettie Page) wearing exotic leather and rubber ensembles, corsets, stockings/garters, boots, and high heels. Gene Bilbrew contributed illustrations to the magazine. The articles, many written by Leonard Burtman, using an alias, covered various aspects of sadomasochism and transvestism, with men depicted as slaves to imperious, all-powerful women. "Exotique" had no nudity, pornographic content, or even sexually suggestive situations. Nevertheless, much like fellow publisher Irving Klaw, in 1957, Burtman would be targeted as a pornographer. He was relentlessly pursued by the U.S. Postal Inspection Service (acting as a censorship agency under the Comstock laws) and local law enforcement (which functioned in coordination with Postal Inspectors and the Catholic Church). Eventually, he was arrested, his magazines and materials confiscated, and brought to trial. This led to the demise of the magazine in 1959. However, starting in 1960, Burtman (under a different imprint) would go on to publish many more fetish magazines that were nearly identical to "Exotique" such as "New Exotique", "Masque", "Connoisseur", "Bizarre Life", "High Heels", "Unique World", "Corporal" (a pioneering spanking-fetish magazine) and others well into the 1970s.

New York photographer Irving Klaw also published illustrated adventure/bondage serials by fetish artists Eric Stanton, Gene Bilbrew, Adolfo Ruiz and others. Klaw is best known for operating an international mail-order business selling photographs and film of attractive women (sometimes in bondage) from the 1940s to the 1960s. His most famous bondage model was Bettie Page, who became the first celebrity of bondage film and photography.

These publications disappeared for a time with a crackdown on pornography in the late 1950s.

The self-medication theory suggests that people with severe mental illnesses misuse substances in order to relieve a specific set of symptoms and counter the negative side-effects of antipsychotic medication.

Khantizan proposes that substances are not randomly chosen, but are specifically selected for their effects. For example, using stimulants such as nicotine or amphetamines can be used to combat the sedation that can be caused by higher doses of certain types of (usually typical) antipsychotic medication. Conversely, some people taking medications with a stimulant effect such as the SNRI antidepressants Effexor (venlafaxine) or Wellbutrin (bupropion) may seek out benzodiazepines or opioid narcotics to counter the anxiety and insomnia that such medications sometimes evoke.

Some studies show that nicotine administration can be effective for reducing motor side-effects of antipsychotics, with both bradykinesia (stiff muscles) and dyskinesia(involuntary movement) being prevented.

From the applied behavior analysis literature, behavioral psychology, and from randomized clinical trials, several evidenced based interventions have emerged: behavioral marital therapy, motivational Interviewing, community reinforcement approach, exposure therapy, contingency management They help suppress cravings and mental anxiety, improve focus on treatment and new learning behavioral skills, ease withdrawal symptoms and reduce the chances of relapse.

In children and adolescents, cognitive behavioral therapy (CBT) and family therapy currently has the most research evidence for the treatment of substance abuse problems. Well-established studies also include ecological family-based treatment and group CBT. These treatments can be administered in a variety of different formats, each of which has varying levels of research support Research has shown that what makes group CBT most effective is that it promotes the development of social skills, developmentally appropriate emotional regulatory skills and other interpersonal skills. A few integrated treatment models, which combines parts from various types of treatment, have also been seen as both well-established or probably effective. A study on maternal alcohol and drug use has shown that integrated treatment programs have produced significant results, resulting in higher negative results on toxicology screens. Additionally, brief school-based interventions have been found to be effective in reducing adolescent alcohol and cannabis use and abuse. Motivational interviewing can also be effective in treating substance use disorder in adolescents.

Alcoholics Anonymous and Narcotics Anonymous are one of the most widely known self-help organizations in which members support each other not to use alcohol. Social skills are significantly impaired in people suffering from alcoholism due to the neurotoxic effects of alcohol on the brain, especially the prefrontal cortex area of the brain. It has been suggested that social skills training adjunctive to inpatient treatment of alcohol dependence is probably efficacious, including managing the social environment.

A number of medications have been approved for the treatment of substance abuse. These include replacement therapies such as buprenorphine and methadone as well as antagonist medications like disulfiram and naltrexone in either short acting, or the newer long acting form. Several other medications, often ones originally used in other contexts, have also been shown to be effective including bupropion and modafinil. Methadone and buprenorphine are sometimes used to treat opiate addiction. These drugs are used as substitutes for other opioids and still cause withdrawal symptoms.

Antipsychotic medications have not been found to be useful. Acamprostate is a glutamatergic NMDA antagonist, which helps with alcohol withdrawal symptoms because alcohol withdrawal is associated with a hyperglutamatergic system.

Psychedelics, such as LSD and psilocin, may have anti-addictive properties.

The past exposure theory suggests that exposure to psychiatric medication alters neural synapses, introducing an that was not previously present. Discontinuation of the drug is expected to result in symptoms of psychiatric illness which resolve once the drug is restarted. This theory suggests that while it may appear that the medication is working, it is only treating a disorder caused by the medication itself. New exposure to psychiatric medication may lead to heightened sensitivity to the effects of drugs and alcohol, which has a deteriorating effect on the patient.

Substance abuse, also known as drug abuse, is a patterned use of a substance (drug) in which the user consumes the substance in amounts or with methods which are harmful to themselves or others.

The drugs used are often associated with levels of intoxication that alter judgment, perception, attention and physical control, not related with medical or therapeutic effects. It is often thought that the main abused substances are illegal drugs and alcohol; however it is becoming more common that prescription drugs and tobacco are a prevalent problem.

Substance-related disorders, including both substance dependence and substance abuse, can lead to large societal problems. It is found to be greatest in individuals ages 18–25, with a higher likelihood occurring in men compared to women, and urban residents compared to rural residents. On average, general medical facilities hold 20% of patients with substance-related disorders, possibly leading to psychiatric disorders later on. Over 50% of individuals with substance-related disorders will often have a "dual diagnosis," where they are diagnosed with the substance abuse, as well as a psychiatric diagnosis, the most common being major depression, personality disorder, anxiety disorders, and dysthymia.

Treatment for confabulation is somewhat dependent on the cause or source, if identifiable. For example, treatment of Wernicke–Korsakoff syndrome involves large doses of vitamin B in order to reverse the thiamine deficiency. If there is no known physiological cause, more general cognitive techniques may be used to treat confabulation. A case study published in 2000 showed that Self-Monitoring Training (SMT) reduced delusional confabulations. Furthermore, improvements were maintained at a three-month follow-up and were found to generalize to everyday settings. Although this treatment seems promising, more rigorous research is necessary to determine the efficacy of SMT in the general confabulation population.

Substance-related disorders were originally subcategorized into "substance use disorders" (SUD) and "substance-induced disorders" (SID). Though DSM-IV makes a firm distinction between the two, SIDs often occur in the context of SUDs.

In psychiatry, confabulation (verb: confabulate) is a disturbance of memory, defined as the production of fabricated, distorted, or misinterpreted memories about oneself or the world, without the conscious intention to deceive. People who confabulate present incorrect memories ranging from "subtle alterations to bizarre fabrications", and are generally very confident about their recollections, despite contradictory evidence.

The usual treatments for overweight individuals is diet and physical exercise.

Dietitians generally recommend eating several balanced meals dispersed through the day, with a combination of progressive, primarily aerobic, physical exercise.

Because these general treatments help most case of obesity, they are common in all levels of overweight individuals.

Drunkorexia is not a medically diagnosed disorder therefore there is no specific treatment. However, as drunkorexia is a combination of two different disorders, binge drinking and eating disorders such as anorexia and bulimia the treatment will need to address both.