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Deep Learning Technology: Sebastian Arnold, Betty van Aken, Paul Grundmann, Felix A. Gers and Alexander Löser. Learning Contextualized Document Representations for Healthcare Answer Retrieval. The Web Conference 2020 (WWW'20)
Funded by The Federal Ministry for Economic Affairs and Energy; Grant: 01MD19013D, Smart-MD Project, Digital Technologies
Clarence and Carl Aguirre (born April 21, 2002) are former conjoined twins born in Silay City, Philippines. They were conjoined at the top of the head (vertical craniopagus). In 2003 they were brought to the United States by their mother Arlene in the hope of having them surgically separated. A revolutionary new process was used in separating the twin boys. Because "marathon" surgical operations have historically led to a high rate of mortality and morbidity, Clarence and Carl's doctors chose to separate them in several smaller operations, allowing the twins to recuperate after each surgery.
In October 2003, tissue expanders (pouches filled with saline) were implanted under the boys' scalps. This is common practice in separating conjoined twins, as it creates more skin that can be used to cover the twins' wounds after separation. Over the next ten months, the brothers underwent several more operations to tease apart their joined skulls and brains. On August 4, 2004, the final surgery was completed. All of these operations were performed at Montefiore Medical Center in the Bronx, New York by a team led by Dr. James T. Goodrich, a pediatric neurosurgeon and Dr. David A. Staffenberg, a plastic surgeon. They received most of their post-operative rehabilitation at Blythedale Children's Hospital in Valhalla, New York (Westchester County).
By December 2005, Clarence could walk short distances unassisted, and Carl could walk with a walker. As of August 2014 both boys and their mother live in a donated house in Scarsdale, New York. The twins continue to attend physical therapy at Blythedale. Goodrich says there was some degeneration of Carl’s right parietal lobe: he takes medication to control seizures, can utter just a word or two at a time, and has limited use of his left arm and leg. Both must still wear helmets to protect their brains; when they are fully grown, their skulls will be patched.
In sports where physical strength is favored, athletes have used anabolic steroids, known for their ability to increase physical strength and muscle mass. The drug mimics the effect of testosterone and dihydrotestosterone in the body. They were developed after Eastern Bloc countries demonstrated success in weightlifting during the 1940s. At the time they were using testosterone, which carried with it negative effects, anabolic steroids were developed as a solution. The drug has been used across a wide range of sports from football and basketball to weightlifting and track and field. While not as life-threatening as the drugs used in endurance sports, anabolic steroids have negative side effects, including:
Side effects in women include:
- hair loss
- male pattern baldness
- hypertrophy of the clitoris
- increased sex drive
- irregularities of the menstrual cycle
- development of masculine facial traits
- increased coarseness of the skin
- premature closure of the epiphysis
In countries where the use of these drugs is controlled, there is often a black market trade of smuggled or counterfeit drugs. The quality of these drugs may be poor and can cause health risks. In countries where anabolic steroids are strictly regulated, some have called for a regulatory relief. Steroids are available over-the-counter in some countries such as Thailand and Mexico.
The Hungerford massacre was a series of random shootings in Hungerford, England, United Kingdom, on 19 August 1987, when Michael Robert Ryan, an unemployed antique dealer and handyman, fatally shot 16 people, including a police officer, before taking his own life. The shootings, committed using a handgun and two semi-automatic rifles, occurred at several locations, including a school he had once attended. 15 other people were also shot but survived. No firm motive for the killings has ever been established, although one psychologist has theorised Ryan's motive for the massacre had been a form of "anger and contempt for the ordinary life" around him, which he himself was not a tangible part of.
A report was commissioned by Home Secretary Douglas Hurd. The Firearms (Amendment) Act 1988 was passed in the wake of the massacre, which bans the ownership of semi-automatic centre-fire rifles and restricts the use of shotguns with a capacity of more than three cartridges. The shootings remain one of the deadliest firearms incidents in British history.
Other forms of synesthesia have been reported, but little has been done to analyze them scientifically. There are at least 80 different types of synesthesia.
Synesthesia is found in at least 4.4% of the population, as a high estimate, which is equivalent to 1 in 23 people. This study had also concluded that one common form of synesthesia—grapheme-color synesthesia (colored letters and numbers) – is found in more than one percent of the population, and this latter prevalence of graphemes-color synesthesia has now been independently verified in a yet larger sample. Earlier estimates of the prevalence of synesthesia were based on "best-guess" estimations only ("e.g." 1 in 250,000) or had limitations in their methodologies because they required synesthetes to refer themselves for study ("e.g." 1 in 2000) and for this reason the authors of those studies had been moderate in their claims. Also, some individuals will not self-classify as synesthetes because they do not realize that their perceptions are different from those of everyone else.
The most common forms of synesthesia are those that trigger colors, and the most prevalent of all is day-color. Also relatively common is grapheme-color synesthesia. We can think of "prevalence" both in terms of how common is synesthesia (or different forms of synesthesia) within the population, or how common are different forms of synesthesia within synesthetes. So within synesthetes, forms of synesthesia that trigger color also appear to be the most common forms of synesthesia with a prevalence rate of 86% within synesthetes. In another study, music-color is also prevalent at 18–41%. Some of the rarest are reported to be auditory-tactile, mirror-touch, and lexical-gustatory.
There is research to suggest that the likelihood of having synesthesia is greater in people with autism.
Islamophobia in Norway refers to the set of discourses, behaviours and structures which express feelings of anxiety, fear, hostility and rejection towards Islam and/or Muslims in Norway. Islamophobia can manifest itself through discrimination in the workforce, negative coverage in the media, and violence against Muslims.
Afro-textured hair is the natural hair texture of certain populations in Africa, the African diaspora, Australia and Asia, which has not been altered by hot combs, flat irons or chemicals (through perming, relaxation or other straightening methods). Each strand of this hair type grows in a tiny, spring-like helix shape. The overall effect is such that, compared to straight, wavy or curly hair, afro-textured hair appears denser.
Cryptomnesia occurs when a forgotten memory returns without it being recognized as such by the subject, who believes it is something new and original. It is a memory bias whereby a person may falsely recall generating a thought, an idea, a tune, or a joke, not deliberately engaging in plagiarism but rather experiencing a memory as if it were a new inspiration.
Islamophobia in the United States can be described as the unvalidated, highly speculative, affective distrust and hostility towards Muslims, Islam, and those perceived as following the religion and or appear as members of the religion and its associative groups. This social aversion and bias is facilitated and perpetuated by violent and uncivilized stereotypes portrayed in various forms of American media networks and political platforms that result in the marginalization, discrimination, and exclusion of the Muslims and Muslim perceived individuals. Media and politicians capitalize on public fear and distrust of Muslims through laws that specifically target Muslims, while the media emphasizes Muslim religious extremism in association with violent activity.
Advocacy groups like Center for American Progress explain that this social phenomenon is not new, but rather, has increased it’s presence in American social and political discourse over the past ten to fifteen years. They cite that several organizations donate large amounts of money to create the “Islamophobia megaphone”. CAP defines the megaphone analogy as “a tight network of anti- Muslim, anti- Islam foundations, misinformation experts, validators, grass root organizations, religious rights groups and their allies in the media and in politics” who work together to misrepresent Islam and Muslims in the United States. As a result of this network, Islam is now one of the most stigmatized religions, with only 37 percent of Americans having a favorable opinion of Islam, according to a 2010 ABC News/ Washington Post poll. This biased perception of Islam and Muslims manifests itself into the discrimination of racially perceived Muslims in the law and media, and is conceptually reinforced by the Islamophobia Network.
Clarence (2012) suggests that afro-textured hair may have initially evolved because of an adaptive need amongst humans' early hominid ancestors for protection against the intense UV radiation of the sun in Africa. With regard to the hypothesized recent African origin of modern humans, the author argues that afro-textured hair was the original hair texture of all modern humans prior to the "Out-of-Africa" migration that populated the rest of the globe. According to Clarence (2012), afro-textured hair may have been adaptive for the earliest modern humans in Africa because the relatively sparse density of such hair, combined with its elastic helix shape, results in an airy effect. The resulting increased circulation of cool air onto the scalp may have thus served to facilitate the body-temperature-regulation system of hominids while they lived on the open savannah. Afro-hair requires more moisture than straight hair and tends to shrink when dry. Instead of sticking to the neck and scalp when damp (as do straighter textures), unless completely drenched it tends to retain its basic springiness. The trait may have been retained and/or preferred among many anatomically modern populations in equatorial areas, such as Polynesians, Micronesians, Melanesians, Australoids and the Negrito, because of its contribution to enhanced comfort levels under tropical climate conditions.
Don Juanism or Don Juan syndrome is a non-clinical term for the desire, in a man, to have sex with many different female partners.
The name derives from the Don Juan of opera and fiction. The term satyriasis is sometimes used as a synonym for Don Juanism. The term has also been referred to as the male equivalent of nymphomania in women. These terms no longer apply with any accuracy as psychological or legal categories of psychological disorder.
The Control of Vibration at Work Regulations 2005, created under the Health and Safety at Work etc. Act 1974. is the legislation in the UK that governs exposure to vibration and assists with preventing HAVS occurring.
Good practice in industrial health and safety management requires that worker vibration exposure is assessed in terms of acceleration amplitude and duration. Using a tool that vibrates slightly for a long time can be as damaging as using a heavily vibrating tool for a short time. The duration of use of the tool is measured as trigger time, the period when the worker actually has their finger on the trigger to make the tool run, and is typically quoted in hours per day. Vibration amplitude is quoted in metres per second squared, and is measured by an accelerometer on the tool or given by the manufacturer. Amplitudes can vary significantly with tool design, condition and style of use, even for the same type of tool.
In the UK, Health and Safety Executive gives the example of a hammer drill which can vary from 6m/s² to 25m/s². HSE publishes a list of typically observed vibration levels for various tools, and graphs of how long each day a worker can be exposed to particular vibration levels. This makes managing the risk relatively straightforward. Tools are given an Exposure Action Value (EAV, the time which a tool can be used before action needs to be taken to reduce vibration exposure) and an Exposure Limit Value (ELV, the time after which a tool may not be used).
In the United States, the National Institute for Occupational Safety and Health published a similar database where values for sound power and vibrations for commonly found tools from large commercial vendors in the United States were surveyed. Further testing is underway for more and newer tools.
The effect of legislation in various countries on worker vibration limits has been to oblige equipment providers to develop better-designed, better-maintained tools, and for employers to train workers appropriately. It also drives tool designers to innovate to reduce vibration. Some examples are the easily manipulated mechanical arm (EMMA) and the suspension mechanism designed into chainsaws.
Focal infection theory is the historical concept that many chronic diseases, including systemic and common ones, are caused by focal infections. In present medical consensus, a focal infection is a localized infection, often asymptomatic, that causes disease elsewhere in the host, but focal infections are fairly infrequent and limited to fairly uncommon diseases. (Distant injury is focal infection's key principle, whereas in ordinary infectious disease, the infection itself is systemic, as in measles, or the initially infected site is readily identifiable and invasion progresses contiguously, as in gangrene.) Focal infection theory, rather, so explained virtually all diseases, including arthritis, atherosclerosis, cancer, and mental illnesses.
An ancient concept that took modern form around 1900, focal infection theory was widely accepted in medicine by the 1920s. In the theory, the "focus of infection" might lead to secondary infections at sites particularly susceptible to such microbial species or toxin. Commonly alleged foci were diverse—appendix, urinary bladder, gall bladder, kidney, liver, prostate, and nasal sinuses—but most commonly were oral. Besides dental decay and infected tonsils, both dental restorations and especially endodontically treated teeth were blamed as foci. The putative "oral sepsis" was countered by tonsillectomies and tooth extractions, including of endodontically treated teeth and even of apparently healthy teeth, newly popular approaches—sometimes leaving individuals toothless—to treat or prevent diverse diseases.
Drawing severe criticism in the 1930s, focal infection theory—whose popularity zealously exceeded consensus evidence—was discredited in the 1940s by research attacks that drew overwhelming consensus of this sweeping theory's falsity. Thereupon, dental restorations and endodontic therapy became again favored. Untreated endodontic "disease" retained mainstream recognition as fostering systemic disease. But only alternative medicine and later biological dentistry continued highlighting sites of dental treatment—still endodontic therapy, but, more recently, also dental implant, and even tooth extraction, too—as foci of infection causing chronic and systemic diseases. In mainstream dentistry and medicine, the primary recognition of focal infection is endocarditis, if oral bacteria enter blood and infect the heart, perhaps its valves.
Entering the 21st century, scientific evidence supporting general relevance of focal infections remained slim, yet evolved understandings of disease mechanisms had established a third possible mechanism—altogether, metastasis of infection, metastatic toxic injury, and, as recently revealed, metastatic immunologic injury—that might occur simultaneously and even interact. Meanwhile, focal infection theory has gained renewed attention, as dental infections apparently are widespread and significant contributors to systemic diseases, although mainstream attention is on ordinary periodontal disease, not on hypotheses of stealth infections via dental "treatment". Despite some doubts renewed in the 1990s by conventional dentistry's critics, dentistry scholars maintain that endodontic therapy can be performed without creating focal infections.
Boanthropy is a psychological disorder in which a human believes himself or herself to be a bovine.
With the 1950s introduction of antibiotics, attempts to explain unexplained diseases via bacterial etiology seemed all the more unlikely. By the 1970s, however, it was established that antibiotics could trigger bacteria's switch to their L phase. Eluding detection by traditional methods of medical microbiology, bacterial L forms and the similar mycoplasma—and, later, viruses—became the entities expected in the theory of focal infection. Yet until the 1980s, such researchers were scarce, largely via scarce funding for such investigations.
Despite the limited funding, research established that L forms can adhere to red blood cells and thereby disseminate from foci within internal organs such as the spleen, or from oral tissues and the intestines, especially during dysbiosis. Perhaps some of Weston Price's identified "toxins" in endodontically treated teeth were L forms, thought nonexistent by bacteriologists of his time and widely overlooked into the 21st century. Apparently, dental infections, including by uncultured or cryptic microorganisms, contribute to systemic diseases.
The most famous sufferer of this disorder is claimed to be Nebuchadnezzar II, who in the Book of Daniel "was driven from men, and did eat grass as oxen". Most probably, the authors were making fun of his aversion to meat or violence.
Carl Jung would subsequently instance 'Nebuchadnezzar...[as] a complete regressive degeneration of a man who has overreached himself'.
According to Persian traditions, the Buyid prince Majd al-Dawla was suffering from an illusion that he is a cow, making the sound of a cow and asking that to be killed so that his flesh could be consumed. He was cured by Avicenna.
The first documented instance of cryptomnesia occurred in 1874 with the medium Stainton Moses.
The word was first used by the psychiatrist Théodore Flournoy, in reference to the case of medium Hélène Smith (Catherine-Élise Müller) to suggest the high incidence in psychism of "latent memories on the part of the medium that come out, sometimes greatly disfigured by a subliminal work of imagination or reasoning, as so often happens in our ordinary dreams."
Carl Gustav Jung treated the subject in his thesis "On the Psychology and Pathology of So-Called Occult Phenomena" (1902) and in an article, "Cryptomnesia" (1905), suggested the phenomenon in Friedrich Nietzsche's "Thus Spoke Zarathustra". The idea was studied or mentioned by Géza Dukes, Sándor Ferenczi and Wilhelm Stekel as well as by Sigmund Freud in speaking of the originality of his inventions.
Anti vibration gloves are traditionally made with a thick and soft palm material to insulate from the vibrations. The protection is highly dependent on frequency range, most gloves provide no protection in palm and wrist below ~50Hz and in fingers below ~400Hz. Factors such as high grip force, cold hands or vibration forces in shear direction can have a reducing effect and or increase damage to the hands and arms. Gloves do help to keep hands warm but to get the desired effect, the frequency output from the tool must match the properties of the vibration glove that is selected. It should be noted that Anti Vibration gloves in many cases amplify the vibrations at frequencies lower than those mentioned in the text above.
In psychiatry, derailment (also loosening of association, asyndesis, asyndetic thinking, knight's move thinking, or entgleisen) is a thought disorder characterized by discourse consisting of a sequence of unrelated or only remotely related ideas. The frame of reference often changes from one sentence to the next.
In a mild manifestation, this thought disorder is characterized by slippage of ideas further and further from the point of a discussion. Derailment can often be manifestly caused by intense emotions such as euphoria or hysteria. Some of the synonyms given above ("loosening of association", "asyndetic thinking") are used by some authors to refer just to a "loss of goal": discourse that sets off on a particular idea, wanders off and never returns to it. A related term is tangentiality—it refers to off-the-point, oblique or irrelevant answers given to questions. In some studies on creativity, "knight's move thinking", while it describes a similarly loose association of ideas, is not considered a mental disorder or the hallmark of one; it is sometimes used as a synonym for lateral thinking.
Early detection of the disease is important, since physical and neurological damage may be irreversible even if cured. Medications can decrease the risk of those living with people with leprosy from acquiring the disease and likely those with whom people with leprosy come into contact outside the home. However, concerns are known of resistance, cost, and disclosure of a person's infection status when doing follow-up of contacts. Therefore, the WHO recommends that people who live in the same household be examined for leprosy and be treated only if symptoms are present.
The Bacillus Calmette–Guérin (BCG) vaccine offers a variable amount of protection against leprosy in addition to tuberculosis. It appears to be 26 to 41% effective (based on controlled trials) and about 60% effective based on observational studies with two doses possibly working better than one. Development of a more effective vaccine is ongoing.
A number of leprostatic agents are available for treatment. For paucibacillary (PB or tuberculoid) cases, treatment with daily dapsone and monthly rifampicin for six months is recommended. While for multibacillary (MB or lepromatous) cases, treatment with daily dapsone and clofazimine along with monthly rifampicin for 12 months is recommended.
Multidrug therapy (MDT) remains highly effective, and people are no longer infectious after the first monthly dose. It is safe and easy to use under field conditions due to its presentation in calendar blister packs. Relapse rates remain low, and no resistance to the combined drugs is seen.
"Entgleisen" (derailment in German) was first used with this meaning by Carl Schneider in 1930. The term "asyndesis" was introduced by N. Cameron in 1938, while "loosening of association" was introduced by A. Bleuler in 1950. The phrase "knight's move thinking" was first used in the context of pathological thinking by the psychologist Peter McKellar in 1957, who hypothesized that schizophrenics fail to suppress divergent associations. "Derailment" was used with this meaning by Kurt Schneider in 1959.
Psychiatrist Carl Jung believed that Don Juanism was an unconscious desire of a man to seek his mother in every woman he encountered. However, he didn't see the trait as entirely negative; Jung felt that positive aspects of Don Juanism included heroism, perseverance and strength of will.
Jung argues that related to the mother-complex "are homosexuality and Don Juanism, and sometimes also impotence. In homosexuality, the son's entire heterosexuality is tied to the mother in an unconscious form; in Don Juanism, he unconsciously seeks his mother in every woman he meets...Because of the difference in sex, a son's mother-complex does not appear in pure form. This is the reason why in every masculine mother-complex, side by side with the mother archetype, a significant role is played by the image of the man's sexual counterpart, the anima."
One of Theodore Millon's five narcissist variations is the amorous narcissist which includes histrionic features. According to Millon, the Don Juan or Casanova of our times is erotic and exhibitionistic.
In October 2015, a Muslim convert named Malika Bayan was turned away from a hair salon in Bryne by a hairdresser named Merete Hodne who said the Bayan's headscarf was "a totalitarian symbol." Hodne also said that Islam was not a religion, but rather a political ideology. Hodne was subsequently charged 10,000 kroner for religious discrimination. Former MP Peter N. Myhre sided with Hodne, arguing a hijab was similar to a Nazi uniform and denounced the court system for convicting her of discrimination. It was revealed by Norwegian media prior to the court ruling that Merete Hodne was once a member of the anti-Islam group PEGIDA.