Abstract
The Clear Cell Renal Cell Carcinoma (CCRCC) is a type of renal cell carcinoma.
Microscopy
Generally, the cells have a clear cytoplasm, are surrounded by a distinct cell membrane and contain round and uniform nuclei.
Genetics | Molecular genetics
Several frequently mutated genes were discovered in CCRCC: VHL, KDM6A/UTX, SETD2, KDM5C/JARID1C and MLL2. PBRM1 is also commonly mutated in CCRCC.